Keywords
Vitamin D
Deficiency
Treatment
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Abstract
Objective: Analyze the relationship between vitamin D levels and the risk of developing RRMS, as well as its immunoregulatory effects and its possible therapeutic contribution. Bibliographic review: Multiple sclerosis (MS) is an inflammatory, autoimmune, demyelinating, and chronic disease of the central nervous system, which predominantly affects young women, being classified into relapsing-remitting MS (RRMS), primary progressive, and secondary progressive. Scientific evidence suggests an association between vitamin D deficiency and an increased risk of developing autoimmune diseases, including RRMS. The studies analyzed indicate that vitamin D plays an important immunomodulatory role, especially through the modulation of T lymphocyte activity, favoring an anti-inflammatory profile and inhibiting cytokines involved in the pathogenesis of MS. Final considerations: These findings suggest a potential role for vitamin D in the treatment of RRMS. However, new clinical trials with larger samples are needed to define ideal doses and more consistently clarify the influence of vitamin D on disease progression.
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