Keywords
Nutritional supplements
Dietary supplements
ADHD
Omega 3
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Abstract
Objective: To present, through scientific evidence, the effects of omega 3 supplementation in children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD). Methods: Theoretical review of the integrative type, comprising studies published in the decade between 2013 and 2022, indexed in PubMed, Latin American and Caribbean Literature in Health Sciences (LILACS) and Medical Literature Analysis and Retrieval System Online (MEDLINE) databases. Original articles were included, in Portuguese, English and Spanish, aligned with the research theme. Six articles were selected to compose this review. Results: Five randomized double-blind clinical studies and one open randomized study were included, which addressed the effects of omega 3 supplementation in children and adolescents. Only one of the studies did not report improvement in any of the evaluated aspects. In the other studies, positive outcomes were presented in at least one of the observed aspects, such as behavior, vision, cognition, work improvement or ADHD symptoms themselves. Final considerations: Although most studies have shown a positive outcome in at least one of the aspects studied, further studies are needed in this area, with a larger number of participants and standardized dosages, so that more conclusive results can be achieved.
References
AL-GHANNAMI S, et al. Randomized open-label trial of docosahexaenoic acid–enriched fish oil and fish meal on cognitive and behavioral functioning in Omani children. Nutrition, 2019; 57:167-172.
AMERICAN PSYCHIATRIC ASSOCIATION. Manual diagnóstico e estatístico de transtornos mentais: DSM-5. 2014. Disponível em: http://www.institutopebioetica.com.br/documentos/manual-diagnostico-e- estatistico-de-transtornos-mentais-dsm-5.pdf. Acessado em: 10 de fevereiro de 2023.
AMSHIDNIA A, et al. Food intake and attention-deficit/hyperactivity disorder in children: A case control study. Clinical nutrition ESPEN, 2021; 44:342-347.
BOS DJ, et al. Reduced Symptoms of Inattention after Dietary Omega-3 Fatty Acid Supplementation in Boys with and without Attention Deficit/Hyperactivity Disorder. Neuropsychopharmacology. 2015; 40(10):2298-306.
BOTELHO LLR, et al. O método da revisão integrativa nos estudos organizacionais. Gestão e Sociedade, 2011; 5(11): 121–136.
BRASIL. Ministério da Saúde. Transtorno do déficit de atenção com hiperatividade. 2014a. Disponível em: https://bvsms.saude.gov.br/transtorno-do-deficit-de-atencao-com-hiperatividade-tdah/ Acessado em: 10 de fevereiro de 2023.
BRASIL. Ministério da Saúde. Guia alimentar para a população brasileira. 2014b. Disponível em: https://bvsms.saude.gov.br/bvs/publicacoes/guia_alimentar_populacao_brasileira_2ed.pdf Acessado em: 10 de fevereiro de 2023.
CORNU C, et al. A double-blind placebo-controlled randomised trial of omega-3 supplementation in children with moderate ADHD symptoms. European child & adolescent psychiatry, 2018; 27(3):377-384.
CRIPPA A, et al. Behavioral and cognitive effects of docosahexaenoic acid in drug-naïve children with attention-deficit/hyperactivity disorder: A randomized, placebo-controlled clinical trial. European Child & Adolescent Psychiatry, 2019; 28(4):571-583.
DINICOLANTONIO JJ, O’KEEFE JH. The importance of marine omega-3s for brain development and the prevention and treatment of behavior, mood, and other brain disorders. Nutrients, 2020; 12(8): 2333.
DRECHSLER R, et al. ADHD: Current concepts and treatments in children and adolescents. Neuropediatrics, 2020; 51(5):315-335.
GENTRY R, et al. Integration of evidence to evaluate the potential for neurobehavioral effects following exposure to USFDA-approved food colors. Food Chem Toxicol, 2021; 151:112097.
GOW RV, et al. Omega-3 fatty acids are related to abnormal emotion processing in adolescent boys with attention deficit hyperactivity disorder. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2013; 88(6):419-429.419-429.
JOHNSON M, et al. Omega 3/6 fatty acids for reading in children: a randomized, double‐blind, placebo‐ controlled trial in 9‐year‐old mainstream schoolchildren in Sweden. Journal of Child Psychology and Psychiatry, 2017; 58(1):83-93.
LAWRENCE K, et al. Trialling a microbiome-targeted dietary intervention in children with ADHD—the rationale and a non-randomised feasibility study. Pilot and Feasibility Studies, 2022; 8(1):108.
MATSUDAIRA T, et al. Biochemical and psychological effects of omega-3/6 supplements in male adolescents with attention-deficit/hyperactivity disorder: A randomized, placebo-controlled, clinical trial. Journal of Child and Adolescent Psychopharmacology, 2015; 25(10):775-82.
MINISTÉRIO DA SAÚDE. Guia alimentar para a população brasileira. 2014. Disponível em: https://bvsms.saude.gov.br/bvs/publicacoes/guia_alimentar_populacao_brasileira_2ed.pdf Acessado em: 10 de fevereiro de 2023.
RODRÍGUEZ-HERNÁNDEZ PJ, et al. Impact of Omega-3 Fatty Acids Among Other Nonpharmacological Interventions on Behavior and Quality of Life in Children with Compromised Conduct in Spain. Journal of Dietary Supplements, 2020; 17(1):1-12.
WIDENHORN-MÜLLER K, et al. Effect of supplementation with long-chain ω-3 polyunsaturated fatty acids on behavior and cognition in children with attention deficit/hyperactivity disorder (ADHD): A randomized placebo-controlled intervention trial. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2014; 91(1-2):49-60.
WU, Qiaoling et al. Protective effects of dietary supplementation with natural ω-3 polyunsaturated fatty acids on the visual acuity of school-age children with lower IQ or attention-deficit hyperactivity disorder. Nutrition, 2015; 31(7-8):935-40.