Keywords
Acute Diarrhea
Rotavirus
Rotavirus Vaccines
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Abstract
Objective: To analyze the impact of the COVID-19 pandemic on human rotavirus vaccination and its consequences. Methods: This study analyzed data obtained from DATASUS for the period between 2018 and 2022, in which vaccination coverage rates, hospitalizations, and mortality related to this pathology were observed. Ethical approval was not required as the data are in the public domain. Results: During the pandemic, various measures were taken to contain the spread of COVID-19, directly impacting the vaccination coverage against human rotavirus, reaching the lowest result since the first years after the implementation of this immunization in 2021 (71.80%). Additionally, during this period, there was also a decrease in the number of hospitalizations due to acute diarrhea caused by rotavirus. Finally, there was a 37% increase in mortality. Conclusion: It was observed that the COVID-19 pandemic negatively impacted human rotavirus vaccination, necessitating the adoption of measures to prevent the loss of herd immunity.
References
BARROS LL, et al. Change in Rotavirus Vaccine Coverage in Brazil from before (2015–2019) through the COVID-19 Pandemic Period (2020–2021). Viruses, 2023, 15: e292: 1-13.
BURNETT E, et al. Global Impact of Rotavirus Vaccination on Childhood Hospitalizations and Mortality From Diarrhea. J Infec Dis, 2017; 215(11): 1666-1672.
BURNETT E, et al. Global Impact of Rotavirus Vaccination on Diarrhea Hospitalizations and Deaths Among Children <5 Years Old: 2006-2019. J Infect Dis, 2020; 222(10): 1731-1739.
CUNLIFFE NA, et al. Efficacy of human rotavirus vaccine against severe gastroenteritis in Malawian children in the first two years of life: a randomized, double-blind, placebo controlled trial. Vaccine, 2012; 1(1): A36-43.
JESUS MCS, et al. Impact of a twelve-year rotavirus vaccine program on acute diarrhea mortality and hospitalization in Brazil: 2006-2018. Expert Rev Vaccines, 2020; 19(6): 585-593.
GBD, Diarrhoeal Diseases Collaborators. Estimates of global, regional, and national morbidity, mortality, and aetiologies of diarrhoeal diseases: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Infect Dis, 2017; 17(9): 909-948.
GBD, 2015 Mortality and Causes of Death Collaborators. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet, 2016; 388(10053): 1459-1544.
GUTIERREZ MB, et al. Rotavirus A during the COVID-19 Pandemic in Brazil, 2020-2022: Emergence of G6P[8] Genotype. Viruses, 2023; 15(8): 1619.
HATOUN J, et al. Social Distancing for COVID-19 and Diagnoses of Other Infectious Diseases in Children. Pediatrics, 2020; 146(4): e2020006460.
BRASIL. Manual do Ministério da Saúde - Secretaria de Atenção Primária à Saúde. Dez Passos para ampliação das coberturas vacinais na atenção primária à saúde. 2019. Disponível em: http://189.28.128.100/dab/docs/portaldab/documentos/folder10pontos.pdf. Acessado em: 17 de outubro de 2023.
BRASIL. Ministério da Saúde - Secretaria de Vigilância em Saúde. Programa Nacional de Imunizações (PNI): 40 anos. 2013. Disponível em: https://bvsms.saude.gov.br/bvs/publicacoes/programa_nacional_imunizacoes_pni4 0.pdf. Acessado em: 17 de outubro de 2023.
PROCIANOY GS, et al. Impacto da pandemia do COVID-19 na vacinação de crianças de até um ano de idade: um estudo ecológico. Ciênc saúde coletiva, 2022; 27(3): 969–78.
RADLOVIC N, et al. Acute Diarrhea in Children. Srp Arh Celok Lek, 2015, 143(11-12):755-62.
SAÚDE. 2023. In: ministério da saúde secretaria de vigilância em saúde e ambiente departamento de inunização e doenças imunopreveníveis. Brasília: Coordenação-Geral de Incorporação Científica e Imunização. Disponível em: https://www.gov.br/saude/pt-br/assuntos/saude-de-a-a-z/c/calendario-nacional-de-vacinacao/calendario-vacinal-2023/calendario-nacional-de-vacinacao-2023-crianca/. Acessado em: 17 de outubro de 2023.
TROEGER C, et al. Rotavirus Vaccination and the Global Burden of Rotavirus Diarrhea Among Children Younger Than 5 Years. JAMA Pediatr, 2018; 172(10): 958-965.
YI-WAI T, et al. Laboratory Diagnosis of COVID-19: Current Issues and Challenges. Journal of Clinical Microbiology, 2020; 58(6): 1-10.