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Association between microcephaly and neurodevelopmental alterations in children diagnosed with Congenital Zika Syndrome (CZS)
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Keywords

Microcephaly
Motor development
Congenital Zika Syndrome

How to Cite

Association between microcephaly and neurodevelopmental alterations in children diagnosed with Congenital Zika Syndrome (CZS). (2025). Revista Eletrônica Acervo Científico, 25, e20538. https://doi.org/10.25248/reac.e20538.2025

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Abstract

Objective: To investigate evidence of associations between microcephaly and neurodevelopmental changes in children exposed to Congenital Zika Syndrome (CZS) infection. Methods: An integrative literature review was conducted in the BVS, SciELO, MEDLINE, and LILACS databases. Standardized descriptors and defined inclusion and exclusion criteria were used to select studies. After analyzing and synthesizing the data, a flowchart was created to describe the methodological steps of the review process. Results: Six articles that met the eligibility criteria were included. Evidence indicates that congenital Zika virus infection is strongly associated with microcephaly and several changes in child neurodevelopment. Among the most frequent are difficulties in the areas of speech and language, visual problems, changes in social skills, impaired cognition and learning, and emotional and behavioral difficulties. Final considerations: Understanding the associations between SCZ and delays in neuropsychomotor development is essential to support scientific debate and guide public health policies, ensuring more effective care strategies for affected children and their families.

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