Abstract
Melasma is acquired chronic hyperpigmentation, affecting photoexposed areas of the skin such as the face and eventually the neck and arms. Since its etiology is multifactorial, the pathogenesis remains unknown, knowing that ultraviolet radiation is the predominant factor. Microneedling or Percutaneous Needle Collagen Induction (IPCA) was recently included as an approach to this pathology. Thus, we sought to gather and discuss scientific data that prove the effectiveness of microneedling associated with Drug delivery in the treatment of female melasma. A literature review was carried out in the main virtual databases, Pubmed, Lilacs, Medline, Scielo and Bireme, of articles published between 2009 and 2019, which addressed the topic. The effectiveness of the combination of the techniques described in skin whitening, hydration and aiding rejuvenation has been demonstrated, however due to the small amount of studies, more publications are needed to better clarify the data.