Abstract
A female patient, 62 years old, with a history of postmenopausal vaginal bleeding, abundant and intermittent, lasting six months, associated with significant weight loss, pelvic pain and voiding difficulty. Complementary exams revealed an expansive lesion in the isthmus and cervix, with signs of bilateral parametrial invasion and superior third of the vagina, in close contact with the bladder and rectum. The biopsy revealed high-grade fusocellular sarcoma. The patient was referred to chemotherapy and neoadjuvant radiotherapy with programming for further surgical treatment. This case corroborates with the thought that although rare, it is important to suggest the possibility of uterine sarcoma in cases of vaginal bleeding after menopause. Histological study and staging are essential to obtain a better therapeutic quality.