Abstract
This article aimed to do a narrative review the impact of hematopoietic stem cell transplantation (HSCT) on the lives of pediatric transplant patients, addressing the main short and long-term problems, as well as the benefits brought by therapy. HSCT is a treatment option that has evolved significantly, thanks to advances in research and technology, being a good alternative for patients who have not been successful in other approaches. The therapy is an aggressive procedure with possible triggering of important physical and mental consequences for the patient. Thus, it is noted that the best way to search for good quality of life for transplanted pediatric patients and their families is to carry out continuous monitoring by a multidisciplinary team for the surveillance of late effects, preventing possible attacks. Thus, together, parents should be properly advised on the possible complications after the procedure and on how to deal with the existing biopsychosocial and economic challenges.