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Effects of deep brain stimulation in patients with Parkinson’s disease: a literature review
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Keywords

Deep brain stimulation
Parkinson’s disease
Motor disorders

How to Cite

Effects of deep brain stimulation in patients with Parkinson’s disease: a literature review. (2021). Revista Eletrônica Acervo Científico, 20, e5019. https://doi.org/10.25248/reac.e5019.2021

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Abstract

This paper proposes a literature review in order to evaluate the effects of such treatment in motor, as well as non-motor symptoms of DP patients. Each patient should be evaluated individually, taking into account the symptoms, the time of disease progression, adverse effects and possible surgical risks. It concludes that regular high-frequecy DBS has been efficient in bradykinesia. Effect on dysphagia were non-conclusive. Verbal fluency is reduced immediately after surgery, what has been attributed to implant-caused microlesions rather to a motor symptom per se. Similarly, dyskinesia and dystonia have shown improvement after DBS, highlighting a necessity to select the right patient profile for the procedure: individuals under seventy, without prior psychiatric issues. Research on non-motor effects preliminarily points to overall security of the procedure, though new studies with refined methodology and statistical analyses are necessary. Minimum cognitive losses immediately after surgery justify the risk against an overall improvement in patients’ quality of life.

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