Abstract
Objective: Report a case of late diagnosis of variable common immunodeficiency, in an elderly patient, with a history of recurrent sinopulmonary infections. Case description: Female patient, 63 years old, civil engineer, with bronchiectasis. Admitted with a productive cough and worsening of baseline dyspnea started two days before medical care. Upon admission, tests showing anemia, significant leukocytosis, platelets and elevated C-reative protein. History of recurrent refractory airway infections, difficult to treat. The investigation of possible causes of structural lung disease (bronchiectasis) began: exams of protein electrophoresis with the presence of hypogammaglobulinemia, in addition to low dosage of IgA and IgM, confirming the hypothesis of common variable immunodeficiency, therefore starting treatment with intravenous immunoglobulin. She was discharged asymptomatic, with an outpatient follow-up schedule and treatment with immunoglobulins every 28 days. She did not recur with sinopulmonary infection within one year after hospital discharge. Final considerations: Immunodeficiency should be considered as a differential diagnosis in patients with recurrent sinopulmonary infections. Early diagnosis allows for immediate treatment, decreasing assimilation to morbidity and providing better quality of life.