Abstract
Objective: To analyze the coagulative disorders that occur in pregnant women infected with SARS-CoV-2, in order to verify which are the factors that predispose pregnant women to the worsening of COVID-19. Bibliographic review: When analyzing whether COVID-19 can influence the coagulative processes that occur physiologically during pregnancy, it was found that the “cytokine storm”, that is, the hyperinflammatory state caused by the virus, contributes to the worsening of the hypercoagulative situation of pregnancy. It was also evident that there is an elevation of D-dimer above the expected for pregnancy, with the formation of placental microthrombi, indicating a worse maternal and fetal prognosis. It was found that there are greater negative outcomes involved, however it is not clear that the disease occurs, necessarily, due to the SARS-CoV-2 infection. Final considerations: There is still a lack of studies on the problems of COVID-19 in pregnant women, however, it is important to emphasize the need for greater attention for these patients, due to the gestational changes that can aggravate the disease.
