Abstract
Objective: Discuss the association between the prevalence of depression in diabetic patients, evaluating epidemiological, psychosocial, pathophysiological aspects and the correct clinical management. Bibliographic review: There was a bidirectional link between diabetes and depression, which is almost twice as prevalent in patients with type 2 diabetes. Findings corroborated by the main pathophysiological hypothesis found, which joins the two disorders, in which the sustained increase in catecholamines in depressive illness would lead to an increase in blood glucose, through a decrease in insulin synthesis or an increase in peripheral resistance to the action of insulin, in addition to the neurochemical effects of diabetes on the central serotonergic, noradrenergic and dopaminergic systems, decreasing the function of these amines. The psychosocial relevance of the disorders present in a concomitant manner, associated with a low quality of life, reduced adherence to prescriptions and self-management, and a greater impact and prevalence of diabetic complications is also perceived, causing an increase in the use and, consequently, in the costs of health. Final considerations: Despite the clear correlation found between such pathologies, there are no large articles with a control group and randomized studies that confirm this association.