Abstract
Objective: Discuss their clinical impacts and associated comorbidities, also addressing therapeutic measures and their effectiveness. Literature review: OHS is a chronic condition given by the association of factors such as hypercapnia, respiratory changes and obesity. Along with OHS, other disorders may arise, such as OSA and cardiovascular alterations, which are correlated with unfavorable outcomes. The treatment of choice for OHSS is CPAP, and a multidisciplinary approach to improving sleep hygiene and lifestyle changes is essential, which are considered essential measures. Final considerations: Through an analysis without systematization and comparison with other available techniques, it was found that the treatment of choice is made with CPAP, due to the reduction in the Apnea-Hypopnea Index (AHI) in most patients, not being association with other therapeutic measures is necessary. Therapies such as tracheostomy and phlebotomy should be performed only if necessary. In addition, medications such as medroxyprogesterone and acetazolamide and excessive use of loop diuretics and sedatives/hypnotics should be avoided.