Abstract
Objetive: Describe and discuss the parameters of ventilatory support of patients with COVID-19, as well as the criteria and methods used for weaning from Invasive Mechanical Ventilation (IMV). Bibliographic review: According to the literary analysis, the controlled pressure ventilation mode with low tidal volume is within the recommended initial parameters for IMV. Weaning, in turn, includes individual factors, such as the load and capacity of the respiratory system, and the psychological, physical and nutritional aspects. In patients with COVID-19, the traditional extubation criteria remain the same, the process being done gradually, encompassing the gradual reduction of the Positive End Expiratory Pressure (PEEP) level while checking the oxygenation targets. In addition, respiratory physiotherapy is necessary before and after extubation. Final considerations: Despite the scarcity of studies and the lack of consensus regarding the management of COVID-19, an effective starting point has been established in the treatment of such patients with regard to IMV parameters and the weaning of such therapy, culminating in the success of such interventions.