Abstract
Objective: To analyze studies on drug intoxication in order to gather the main treatments and antidotes used, aiming to contribute to future research directions. Methods: This is a literature review, whose articles were selected from the PubMED, SciELO and LILACS databases, published from the year 2015, in English, Spanish or Portuguese. Results: a total of 2092 articles were found. After applying the exclusion and inclusion criteria, we obtained 17 articles to compose the sample. Among the selected studies, paracetamol intoxication was most reported. Vital support to the patient should be prioritized. Activated charcoal, gastric lavage, and urine alkalinization were the most found forms of treatment, with hemodialysis, hemoperfusion, and lipid infusion being alternative therapies. In addition, the main known antidotes for some specific intoxications were listed. Final considerations: Drug intoxication is a worldwide problem, and prevention policies are necessary in order to avoid the growth of the self-medication.