Keywords
Otorhinolaryngology
Drug treatment
How to Cite
Copyright © | All rights reserved.
The journal holds the exclusive copyright for the publication of this article under the terms of Brazilian law 9610/98.
Partial reproduction
The use of parts of the texts, figures and questionnaire of the article is free, being mandatory the citation of the authors and journal.
Total reproduction
It is expressly prohibited and must be authorized by the journal.
Abstract
Objective: To synthesize the problem of Gastroesophageal Reflux Disease (GERD) and its extra-esophageal clinical repercussions in otorhinolaryngology. Methods: It is an exploratory narrative literature review. The construction steps of this review were: selecting the theme and research question, searching for articles in digital databases from 2015 to 2021, applying inclusion and exclusion criteria in the sample, in addition to discussing the results presented by the articles. Results: The pathology presents important extra-esophageal clinical signs and symptoms such as: cough, hoarseness, laryngitis, dental erosion, obstructive sleep apnea, sinusitis and or chronic rhinitis, among others within otorhinolaryngology. The drug treatment of the disease and its effectiveness in resolving these symptoms were also addressed. In addition to medications such as proton pump inhibitors, lifestyle change is critical. Final considerations: It is very important for the physician to understand that GERD generates important otorhinolaryngological symptoms that directly impact the patient's quality of life, and that they must be taken into account in their treatment for it to be effective.
References
AKINOLA MA, et al. Gastroesophageal reflux disease: prevalence and Extraesophageal manifestations among undergraduate students in South West Nigeria. BMC Gastroenterology, 2020; 20:160.
ANTUNES C, et al. Doença do refluxo gastroesofágico. National Library of Medicine, 2021; 1-8.
AZZAM RS. Are the persistent symptoms to proton pump inhibitor therapy due to refractory gastroesophageal reflux disease or to other disorders?. Arq Gastroenterol, 2018; 55(1):85-91.
BASOGLU OK, et al. Síndrome da apnéia obstrutiva do sono e doença do refluxo gastroesofágico: a importância da obesidade e gênero. Respiração do sono, 2015; 19 (2): 585–592.
CESÁRIO S, et al. Diagnóstico de DRGE em manifestações típicas e atípicas. Acta Biomed, 2018; 89 (8-S): 33-39.
CHUANG TW, et al. Current status of gastroesophageal reflux disease: diagnosis and treatment. Acta Gastroenterologia Bélgica, 2017; 80(3):396-404.
COSSÍO SS, et al. La búsqueda del Grial: una carrera por la supresión ácida. Revista de Gastroenterología de México, 2019; 84(3):344-356.
DAI FY, et al. Associação de pepsina e danos de DNA no refluxo laringofaríngeo relacionado a pólipos de prega. American Journal of Otolaryngology, 2020; 10268.
DICKMAN R, et al. Unmet Needs in the Treatment of Gastroesophageal Reflux Disease. Journal of Neurogastroenterology and Motility, 2015; 21(3): 309-219.
DURAZZO M, et al. Extra-Esophageal Presentation of Gastroesophageal Reflux Disease: 2020 Update. Journal of Clinical Medicine, 2020; 1-21.
HAIT EJ, MCDONALD DR. Impact of Gastroesophageal Reflux Disease Mucosal Immunity and Atopic Disorders. Clin Rev Allergy Immunol, 2019; 57(2):213-225.
JUNAID M, et al. Doença do Refluxo Laringofaríngeo: Resultado dos Pacientes Após Tratamento nas Clínicas de Otorrinolaringologia. Cureus, 2020; 12 (12): e12195.
KAHRILAS PJ, et al. Tosse Crônica Devido ao Refluxo Gastroesofágico em Adultos. CHEST Journal, 2016; 150 (6): 1341-1360.
KATLE EJ, et al. Gastro-oesophageal reflux in patients with chronic rhino-sinusitis investigated with multichannel impedance - pH monitoring. Rhinology, 2017; 55(1):27-33.
LEASON SR, et al. Association Of Gastro-oesophageal reflux and chronic rhinosinusitis: systematic review and meta-analysis. Rhinology. 2017; 55(1):3-16.
LECHIEN JR, et al. Laryngopharyngeal Reflux: A State-of-the-Art Algorithm Management for Primary Care Physicians. Journal of Clinical Medicine, 2020; 9(11):3618.
LECHIEN JR, et al. Perceptual, Aerodynamic, and Acoustic Characteristics of Voice Changes in Patients with Laryngopharyngeal Reflux Disease. Ear Nose & Throat Journal, 2019; 98(6):E44-E50.
NOUR E, et al. Le reflux gastro-oesophagien acide nocturne pathologique. a propos d’une série pHmétrique. LA TUNISIE MEDICALE, 2015; 93(4):1-5..
PICOS A, et al. Dental erosion in gastroesophageal reflux disease. A systematic review. Clujul Med. 2018; 91(4):387-390.
RAMACHANDRAN A, et al. Incidence and Pattern of Dental Erosion in Gastroesophageal Reflux Disease Patients. J Pharm Bio allied Sci. 2017; 9 (Suppl 1):S138-S141.
SELLA GCP, et al. Relation between chronic rhinosinusitis and gastroesophageal reflux in adults: systematic review. Braz J Otorhinolaryngol. 2017; 83(3):356-363.
SILVA CE, et al. Reflux Laryngitis: Correlation between the Symptoms Findings and Indirect Laryngoscopy. Int Arch Otorhinolaryngol, 2015; 19(3):234-7.
TRAD KS, et al. Transoral Incisionless Fundoplication Effective in Eliminating GERD Symptoms in Partial Responders to Proton Pump Inhibitor Therapy at 6 Months: The TEMPO Randomized Clinical Tria. Surgical Innovation, 2015; 22(1): 26–40.
VAEZI MF, et al. Extraesophageal Symptoms and Diseases Attributed to GERD: Where is the Pendulum Swinging Now? Clin Gastroenterol Hepatol. 2018; 16(7):1018-1029.
WARSI I, et al. Fatores de risco associados a manifestações orais e impacto na saúde bucal da doença do refluxo gastroesofágico: um estudo transversal multicêntrico no Paquistão. BMJ Open. 2019; 9 (3): e021458.
YAN S, et al. Gastroesophageal Reflux Disease: A Cause for Eustachian Tube Dysfunction in Obstructive Sleep Apnea. Ear Nose Throat J, 2020; 4:145561320931219.
ZHANG J, et al. Knowledge of laryngopharyngeal reflux disease among otolaryngologists in 3A hospitals in Beijing. Journal of International Medical Research, 2019; 48(3): 1–6.