Musculoskeletal symptoms associated with long COVID

Article Sidebar

PDF (Português (Brasil))
Published Mar 18, 2025
DOI https://doi.org/10.25248/reac.e19093.2025

Main Article Content

Ana Lívia Oliveira
Centro Univeritário FG
Cailane Vitória Sousa Novaes
Centro Univeritário FG
Gabriel Brenno Costa Barreto Cardoso
Centro Univeritário FG
Ione Fernanda Lemos Fontes
Centro Univeritário FG
Joyce de Souza Miranda
Centro Univeritário FG
João Pedro Alves Nascimento
Centro Univeritário FG
Maria Eduarda Rodrigues de Oliveira
Centro Univeritário FG
Rodrigo Alcântara Normanha
FIP
Vanessa Cristina Teixeira
Centro Univeritário FG
Tarcísio Viana Cardoso
Centro Univeritário FG

Abstract

Objective: To review evidence on musculoskeletal symptoms associated with long COVID-19, in order to understand its impact on the affected population. Methods: An integrative literature review was systematized in the National Library of Medicine (NLM) – PubMed, Scientific Electronic Library Online (SciELO), Latin American and Caribbean Literature in Health Sciences (Lilacs), Medical Literature Analysis and Retrieval System Online (Medline) and Scopus databases, following the six-step protocol for conducting the research. In this scenario, standardized descriptors and exclusion/inclusion criteria were used. The studies were carefully selected and using a protocol, and the review table and flowchart containing the steps taken until selection for review were prepared. Results: Six articles were selected, all published between 2021 and 2024, which met the eligibility criteria. Final considerations: A relationship was observed between Long COVID and musculoskeletal symptoms, compromising the quality of life of survivors.

Article Details

How to Cite
OliveiraA. L., NovaesC. V. S., CardosoG. B. C. B., FontesI. F. L., MirandaJ. de S., NascimentoJ. P. A., OliveiraM. E. R. de, NormanhaR. A., TeixeiraV. C., & CardosoT. V. (2025). Musculoskeletal symptoms associated with long COVID. Revista Eletrônica Acervo Científico, 25, e19093. https://doi.org/10.25248/reac.e19093.2025
Issue
Vol 25 (2025): Revista Eletrônica Acervo Científico (ISSN 2595-7899) | Volume 25 | 2025
Section
Artigos

Copyright © | All rights reserved.

The journal holds the exclusive copyright for the publication of this article under the terms of Brazilian law 9610/98.

Partial reproduction
The use of parts of the texts, figures and questionnaire of the article is free, being mandatory the citation of the authors and journal.

Total reproduction
It is expressly prohibited and must be authorized by the journal.

References

1. ABDULLAHI A, et al. Neurological and Musculoskeletal Features of COVID-19: A Systematic Review and Meta-Analysis. Frontiers in Neurology, 2020; 11: 687.

2. CARDEMIL CV, et al. Incidência, etiologia e gravidade da gastroenterite aguda entre pacientes prospectivamente inscritos em 4 hospitais e centros ambulatoriais para casos de veteranos, 2016-2018. Clin Infect Dis. 2021; 73: 2729–2738.

3. COLLANTES MEV, et al. Neurological manifestations in COVID-19 infection: A systematic review and meta-analysis. Can J Neurol Sci. 2021; 48: 66–76.

4. ELLIOTT AM, et al. The epidemiology of chronic pain in the community. Lancet. 1999; 354(9186): 1248-52.

5. EVCIK D. Musculoskeletal involvement: COVID-19 and post COVID 19. Turkish Journal of Physical Medicine and Rehabilitation, 2023; 1(1): 1–7.

6. GIORGIO MR, et al. The impact of SARS-CoV-2 on skeletal muscles. Acta Myol. 2020; 39: 307–312.

7. IZCOVICH A, et al. Adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir when used for COVID-19: systematic review and meta-analysis of randomised trials. 2022: 12: 48502BMJ.

8. KARAASLAN F, et al. Effects of COVID-19 Pandemic on Turkish Private Practice Dentists' Economic Well-Being. Usak UniversityAcademic Data Management System, 2021.

9. MATA MS, et al. Dor e funcionalidade na atenção básica à saúde. Cienc Saúde Coletiva. 2011; 16(1): 221-30.

10. MENDES KDS, et al. Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & Contexto - Enfermagem, 2008; 17(4): 758–764.

11. OMS. ORGANIZAÇÃO MUNDIAL DA SAÚDE. OMS emite definição oficial da condição pós-COVID-19. 2021.
Nações Unidas Brasil. Disponível em: https ://brasil.un.org/pt-br/150668-oms-emite-definicao-clinica-oficial-da-condicao-pos-covid-19. Acesso em: 24 mar. 2024.

12. PORTILLA EJP, et al. Una revisión de literatura del síndrome pos-covid-19. Educación Médica Superior, Habana, 2022; 36(3).

13. PUNNETT L e WEGMAN DH. Work-related musculoskeletal disorders: the epidemiologic evidence and the debate. J Electromyogr Kinesiol. 2004; 14(1): 13-23.

14. SANTOS PK, et al. The Musculoskeletal Involvement After Mild to Moderate COVID-19 Infection. Frontiers in Physiology, 2022; 13: 813924.

15. SAPRA L, et al. Long-term implications of COVID-19 on bone health: Pathophysiology and therapeutics. Inflamm Res. 2022; 71: 1025–1040.

16. SOUZA MT, et al. Revisão integrativa: o que é e como fazer. einstein (São Paulo), São Paulo, 2010; 8(1): 102-106.

17. SWARNAKAR R, et al. Musculoskeletal complications in long COVID-19: A systematic review. World Journal of Virology, 2022; 11(6): 485–495.

18. TSENG YH e CHEN TH. Cuidados para pacientes com doenças neuromusculares na era da pandemia de COVID-19. Frente. Neurol. 2021; 12: 607790.

19. TUZUN S, et al. Assessment of musculoskeletal pain, fatigue and grip strength in hospitalized patients with COVID-19. Eur J Phys Rehabil Med. 2021; 57: 653–662.

20. VARGHESE J, et al. Sintomas persistentes e anormalidades laboratoriais em pacientes que se recuperaram de COVID-19. Ciência.