Eosinophilic esophagitis: a chronic inflammatory condition of the esophagus
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Abstract
Objective: To highlight data from the literature on eosinophilic esophagitis in order to expand, promote and carry out a process of updating the subject for doctors and medical students, aiming at a better learning about the pathology and better conducts in the face of positive diagnoses. Bibliographic review: Eosinophilic esophagitis (EEo) is an immune-mediated chronic inflammatory condition of the esophageal mucosa, whose main characteristic is the loss of integrity of the esophageal mucosa barrier. The pathogenesis of EoE is related to genetic, environmental and immune system factors of the patient, connected to an atypical inflammatory response mediated by type 2 adaptive T helper cells (Th2) that produce cytokines such as interleukins IL4, IL5 and IL-13. Final considerations: EEo is a pathology that is difficult to diagnose due to the fact that it expresses symptoms similar to gastroesophageal reflux disease (GERD), which, when present, must be treated quickly, in order to avoid functional impairment and promote a better quality of life. life for these patients.
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