Medical management in the face of Aplastic Anemia in puberty: case report

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Published Feb 21, 2023
DOI https://doi.org/10.25248/reamed.e12179.2023

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Ana Victória de Araújo Lustosa
Unifran
Vitória Pereira Cabral de Oliveira
Paula Toledo Tartuci
Alvaro Siqueira Ribeiro Lima
Gabriela Accorsi Bonilha
Carla Alexandra Nasser Barbosa Furtado
Andréa de Oliveira Cecchi
Ana Carolina Eleutério Pirone

Abstract

Objective: To present a favorable outcome of an adolescent diagnosed with aplastic anemia, which benefited from treatment with cyclosporine, rabbit antithymocyte globulin, and a support treatment. Case report: Patient, female, 12 years old, with hemorrhagic manifestations and abnormalities in the blood count generating diagnostic hypothesis of aplastic anemia. Laboratory and histological investigations found results of pancytopenia with medullary hypocellularity, without showing atypical cells nor showing any dysplasias, AA -disease compatible. By defining the diagnosis, cyclosporine therapy was in addition to rabbit antithymocyte globulin and support treatment. Final considerations: Aplastic anemia is a disorder that affects both sexes and may be constitutional or acquired, related to various etiologies such as exposure to drugs, infections, radiation, among others. It is a condition that varies from moderate to very severe and needs rapid and competent diagnosis. Treatment is based on immunomodulation, considering the fact that aplasia anemia is directly caused by the action of the immune system on the multipotent hematopoietic cells of the individual. Finally, in addition to the base treatment, it is very important to institute support with hemoderivative replacement for stabilization of the condition and decreased grievances

Article Details

How to Cite
LustosaA. V. de A., OliveiraV. P. C. de, TartuciP. T., LimaA. S. R., BonilhaG. A., FurtadoC. A. N. B., CecchiA. de O., & PironeA. C. E. (2023). Medical management in the face of Aplastic Anemia in puberty: case report. Revista Eletrônica Acervo Médico, 23(2), e12179. https://doi.org/10.25248/reamed.e12179.2023
Issue
Vol 23 No 2 (2023): Revista Eletrônica Acervo Médico (ISSN 2764-0485) | Volume 23 (2) | 2023
Section
Estudos de Caso

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