Keywords
Respiratory syncytial virus infections
Bronchiolitis obliterans
Caregivers
How to Cite
Copyright © | All rights reserved.
The journal holds the exclusive copyright for the publication of this article under the terms of Brazilian law 9610/98.
Partial reproduction
The use of parts of the texts, figures and questionnaire of the article is free, being mandatory the citation of the authors and journal.
Total reproduction
It is expressly prohibited and must be authorized by the journal.
Abstract
Objective: To analyze the characteristics of Acute Viral Bronchiolitis (AVB) and Bronchiolitis Obliterans (BO). Literature review: AVB is mainly caused by the respiratory syncytial virus, has a seasonal pattern of incidence, which was influenced by the Covid-19 pandemic. It can be caused by viral co-infections, which seems to require a longer period of hospitalization and the identification of serious cases has been facilitated with the use of bedside ultrasound. Treatment is supportive. BO is a chronic lung disease that affects the patient's quality of life; its pathogenesis is not fully known, which makes it difficult to develop an effective therapy. It can hinder the success of lung transplants and requires the patient and their caregivers to adapt their routine in order to guarantee the necessary support in the face of this irreversible condition. Final considerations: It is necessary to encourage more studies focused on these diseases. Furthermore, it is essential that health professionals have a good understanding of them, so that they can assist in managing the child and their guardians, taking into account their particularities.
References
ALMEIDA GC, et al. Constrictive bronchiolitis secondary to exposure to flavoring agents: a little known occupational hazard. Jornal Brasileiro de Pneumologia, 2023; 49(1): 20220328.
ARMATI M, et al. Collagen Type IV Alpha 5 Chain in Bronchiolitis Obliterans Syndrome After Lung Transplant: The First Evidence. Lung, 2023; 201(4): 363-369.
ATAMARI-ANAHUI N, et al. Postinfectious bronchiolitis obliterans in children: case series at a pediatric hospital in Peru. Boletín médico del Hospital Infantil de México, 2023; 80(5): 312-319.
BERMÚDEZ-BARREZUETA L, et al. Outcomes of viral coinfections in infants hospitalized for acute bronchiolitis. Virology journal, 2023; 20(1): 235.
COZZI G, et al. SARS-CoV-2-related bronchiolitis: a multicentre international study. Archives of disease in childhood, 2023; 108(9): 15.
CUI Z, et al. Worldwide Bronchiolitis obliterans research: A bibliometric analysis of the published literature between 2002 and 2022. Medicine (Baltimore), 2023; 102(28): 34263.
HERTER EC, et al. Management of bronchiolitis and recurrent wheezing in preschoolers. Jornal Brasileiro de Pneumologia, 2023; 49(5): 20230298.
JERKIC SP, et al. Association between Polyunsaturated Fatty Acid Profile and Bronchial Inflammation in Bronchiolitis Obliterans. Mediators of inflammation, 2023: 3406399.
JIN Y, et al. Role of the cAMP-PKA-NF-kB pathway in Mucin1 over-expression in A549 cells during Respiratory syncytial virus infection. BMC infectious diseases, 2023; 23(1): 845.
LIAO M, et al. Insight on immune cells in rejection and infection postlung transplant. Immunity, inflammation and disease, 2023; 11(7): 868.
LUISI F, et al. Azithromycin administered for acute bronchiolitis may have a protective effect on subsequent wheezing. Jornal Brasileiro de Pneumologia, 2020; 46(3): 20180376.
MARZUILLO P, et al. Acute kidney injury in infants hospitalized for viral bronchiolitis. European journal of pediatrics, 2023; 182(8): 3569-3576.
MILBRATH VM, et al. Vulnerabilidades vivenciadas por familiares/ cuidadores de crianças com condição crônica. Physis, 2023; 33.
NIEVAS-SORIANO BJ, et al. Worldwide research trends on bronchiolitis in pediatrics. Pediatric pulmonology, 2023; 58(8): 2189-2203.
PEREIRA EQ, et al. Temporal-spatial analysis of hospitalizations for bronchiolitis in Brazil: prediction of epidemic regions and periods for immunization against the Respiratory Syncytial Virus. Revista Paulista de Pediatria, 2023; 41: 2021304.
RYBAK A, et al. Respiratory Syncytial Virus in Outpatient Children with Bronchiolitis: Continuous Virus Circulation During the Nonepidemic Period. Pediatric infectious disease journal, 2023; 42(12): 488-490.
SABEENA S, et al. The impact of coronavirus disease 2019 pandemic on bronchiolitis(lower respiratory tract infection) due to respiratory syncytial virus: A systematic review and meta-analysis. Indian Journal of Public Health, 2023; 67(2): 284-291.
SARRIA EE, et al. Health-related quality of life in post-infectious bronchiolitis obliterans: agreement between children and their proxy. Jornal de pediatria, 2018; 95(5): 614-618.
SMITH JA, et al. Association of outcomes in point-of-care lung ultrasound for bronchiolitis in the pediatric emergency department. American journal of emergency medicine, 2024; 75: 22-28.
SZUPIENKO S, et al. Nebulised 3% hypertonic saline versus 0.9% saline for treating patients hospitalised with acute bronchiolitis: protocol for a randomised, double-blind, multicentre trial. BMJ Open, 2023; 13(11): 080182.
WANG X, et al. Effects of respiratory flora regulation on microbial environment and IL-10/STAT3 signaling pathway in the bronchiolitis obliterans after lung transplantation. Cellular and molecular biology (Online), 2023; 69(10): 201-206.
WU Z, et al. Transcriptome analysis reveals the impact of NETs activation on airway epithelial cell EMT and inflammation in bronchiolitis obliterans. Scientific reports(Nature Publishing Group), 2023; 13(1): 19226.