Keywords
Osteoarthritis
Viscossuplementation
How to Cite
Copyright © | All rights reserved.
The journal holds the exclusive copyright for the publication of this article under the terms of Brazilian law 9610/98.
Partial reproduction
The use of parts of the texts, figures and questionnaire of the article is free, being mandatory the citation of the authors and journal.
Total reproduction
It is expressly prohibited and must be authorized by the journal.
Abstract
Objective: To analyze whether viscosupplementation is truly effective in treating symptoms of hip osteoarthritis. Methods: This is an integrative literature review, conducted through the analysis of original articles found in the PubMed Central (PMC), Virtual Health Library (VHL) and Scientific Electronic Library Online (SciELO) databases using the combination of the descriptors: “Viscosupplementation,” “Osteoarthritis,” “Hyaluronic Acid,” and “Hip” with the boolean operator “AND.” Inclusion criteria included studies published in English, Portuguese, and Spanish in the past five years, with open access. Incomplete and duplicate studies were excluded. Results: The results of this review indicated that, overall, viscosupplementation with hyaluronic acid is indeed effective in treating symptoms caused by osteoarthritis, such as pain and joint function. Additionally, no adverse events or infections were reported. However, it is important to note that this type of treatment does not address the underlying cause of joint destruction, serving instead as symptomatic relief. Final considerations: Viscosupplementation has proven to be an effective and promising procedure for the treatment of osteoarthritis. Therefore, it is crucial for healthcare professionals to have mastery and continuous updates on this topic.
References
ABATANGELO G, et al. Hyaluronic acid: redefining its role. Cells, 2020; 9(7): 1743.
BATTAGLIA AG, et al. Ultrasound-Guided Hip Injections with High Density Hyaluronic Acid: Outcome at One Year Follow Up. Journal of Clinical Medicine, 2024; 13(9): 2515.
DE LUCIA O, et al. Effectiveness and tolerability of repeated courses of viscosupplementation in symptomatic hip osteoarthritis: a retrospective observational cohort study of high molecular weight vs. medium molecular weight hyaluronic acid vs. no viscosupplementation. Frontiers in Pharmacology, 2019; 10: 1007.
DE REZENDE MU e DE CAMPOS GC. Viscosupplementation. Revista Brasileira de Ortopedia, 2012; 47(2): 160-164.
GARCÍA-BRAVO AM, et al. Inyección intrarticular única ecoguiada de ácido hialurónico en la coxartrosis sintomática: estudio retrospectivo de la eficacia de dos presentaciones. Revista de la Sociedad Española del Dolor, 2022; 29(3): 140-148.
IBGE. INSTITUTO BRASILEIRO DE GEOGRAFIA E ESTATÍSTICA. Censo Demográfico 2022: Resultados Preliminares. Rio de Janeiro: IBGE, 2023. Disponível em: https ://www.ibge.gov.br/. Acessado em: 6 de novembro de 2024.
ITO CB, et al. Causas, consequências e tratamento da osteoartrite do joelho e quadril: revisão sistemática. Arquivos do MUDI, 2019; 23(3): 455-466.
KOYANO G, et al. Intra-articular Injections of Cross-linked Hyaluronic Acid in Japanese Patients with Symptomatic Osteoarthritis of the Hip. Progress in Rehabilitation Medicine, 2021; 6: 20210038.
LA GATTA A, et al. Hyaluronan and derivatives: An in vitro multilevel assessment of their potential in viscosupplementation. Polymers, 2021; 13(19): 3208.
LINK TM, et al. Osteoarthritis: MR imaging findings in diferente stages of disease and correlation with clinical findings. Radiology, 2003; 226: 373-381.
MAKVANDI P, et al. A hyaluronic acid-based formulation with simultaneous local drug delivery and antioxidant ability for active viscosupplementation. ACS omega, 2022; 7(12): 10039-10048.
MARINHO A, et al. Hyaluronic acid: A key ingredient in the therapy of inflammation. Biomolecules, 2021; 11(10): 1518.
MIGLIORE A, et al. Efficacy of a single intra-articular HYMOVIS ONE injection for managing symptomatic hip osteoarthritis: a 12-month follow-up retrospective analysis of the ANTIAGE register data. Orthopedic Research and Reviews, 2020; 19-26.
MOREIRA M, et al. Anti-inflamatórios não esteróides tópicos no tratamento da dor por osteoartrose do joelho–Uma revisão baseada na evidência. Revista Portuguesa de Medicina Geral e Familiar, 2014; 30(2): 102-8.
MOTA LMH, et al. Consenso 2012 da Sociedade Brasileira de Reumatologia para o tratamento da artrite reumatoide. Revista Brasileira de Reumatologia, 2012; 52: 152-174.
OMETTI M, et al. The efficacy of intra-articular HYADD4-G injection in the treatment of femoroacetabular impingement: results at one year follow up. Journal of drug assessment, 2020; 9(1): 159-166.
PEREIRA HLA, et al. Tratamento com antiinflamatórios tópicos na osteoartrite de joelho. Revista Brasileira de Reumatologia, 2006; 46: 188-193.
REZENDE MU e GOBBI RG. Tratamento medicamentoso da osteoartrose do joelho. Revista Brasileira de Ortopedia, 2009; 44: 14-19.
REZENDE MU, et al. Improvements in hip osteoarthritis with lavage, triamcinolone and Hylan G-F20. Acta Ortopédica Brasileira, 2020; 28(6): 280-286.
ROSIS RG, et al. Osteoartrite: avaliação clínica e epidemiológica de pacientes idosos em instituição de longa permanência. Rev Bras Clin Med, 2010; 8(2): 101-8.
SANTOS JPM, et al. Análise da funcionalidade de idosos com osteoartrite. Fisioterapia e Pesquisa, 2015; 22(2): 161-168.
SAY KG. Associação entre a presença de citocinas, medidas morfológicas articulares e controle sensório-motor de indivíduos portadores de osteoartrite grau I e II. Tese (Doutorado) - Universidade Federal de São Carlos, 2010; 148.
SCATURRO D, et al. Hybrid hyaluronic acid versus high molecular weight hyaluronic acid for the treatment of hip osteoarthritis in overweight/obese patients. Journal of Functional Morphology and Kinesiology, 2022; 7(1): 20.
SCHIAVI P, et al. Efficacy and safety of viscosupplementation with hyaluronic acid for hip osteoarthritis: results from a cross-sectional study with a minimum follow-up of 4 years. Acta Bio Medica: Atenei Parmensis, 2020; 91: 14.
STEINMETZ JD, et al. Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet Rheumatology, 2023; 5(9): 508-522.
VELASCO-SALGADO C, et al. The Role of Polymeric Biomaterials in the Treatment of Articular Osteoarthritis. Pharmaceutics, 2022; 14(8): 1644.