Abstract
Objective: To describe the epidemiological profile of patients with COVID-19 who progressed to more severe cases of the disease and required hospitalization in the Intensive Care Unit (ICU) of a hospital in Juiz de Fora - MG and to correlate such characteristics with the clinical outcome of the patient. Methods: This is an observational and cross-sectional study, in which medical records of patients with COVID-19 admitted to the ICU of a hospital in Juiz de Fora - MG, from April 2020 to October 2020 were analyzed. Results: Higher hospitalization rates were observed in males (62.7%) and the most frequently observed comorbidity was systemic arterial hypertension (67.3%). The chi-square test of independence showed that there is an association between death and the patient's age group. The presence of comorbidities did not prove to be a predictive factor for greater severity, since the ANOVA tests did not show statistically significant differences, with the sample size being an important limiting factor for this analysis. Conclusion: The highest risk of severe cases and deaths from COVID-19 was observed in elderly individuals, which enables the development of appropriate professional conduct for this specific group, preventing unfavorable outcomes.
References
APICELLA M, et al. COVID-19 in people with diabetes: understanding the reasons for worse outcomes. The Lancet Diabetes & Endocrinology, 2020; 9: 782-92.
BARBOSA IR, et al. Incidence of and mortality from COVID-19 in the older Brazilian population and its relationship with contextual indicators: an ecological study. Revista Brasileira de Geriatria e Gerontologia, 2020; 23(1): e 200171.
ESCOSTEGUY CC, et al. COVID-19: a cross-sectional study of suspected cases admitted to a federal hospital in Rio de Janeiro, Brazil, and factors associated with hospital death. Epidemiologia e Serviços de Saúde, 2021; 30(1): e2020750.
GALVÃO MHR e RONCALLI AG. Factors associated with increased risk of death from COVID-19: a survival analysis based on confirmed cases. Revista Brasileira de Epidemiologia. 2020; 23: e200106.
GENG J, et al. Chronic Diseases as a Predictor for Severity and Mortality of COVID-19: A Systematic Review With Cumulative Meta-Analysis. Frontiers in Medicine, 2021; 1 (8): 588013.
GOMES R, et al. Why do men use health services less than women? Explanations by men with low versus higher education. Caderno de Saúde Pública, 2007; 23(3): 565–74.
GUAN W, et al. Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis. European Respiratory Journal, 2020; 55(5): e2000547.
HUANG C, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet, 2020; 395(10223): 497-506.
JAIN V e YUAN JM. Predictive symptoms and comorbidities for severe COVID-19 and intensive care unit admission: a systematic review and meta-analysis. International Journal of Public Health, 2020; 65: 533–46.
KUMAR A, et al. Is diabetes mellitus associated with mortality and severity of COVID-19? A meta-analysis. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 2020; 14(4): 535-45.
LI LQ, et al. COVID-19 patients clinical characteristics, discharge rate, and fatality rate of meta-analysis. Journal of Medical Virology, 2020; 92(6): 577-583.
LIU Y, et al. Clinical features and progression of acute respiratory distress syndrome in coronavirus disease 2019. 2020.
PAIVA KM, et al. Prevalence and Associated Factors of SARS by Covid-19 in Adults and Aged People with Chronic Cardiovascular Disease. Arquivos Brasileiros de Cardiologia, 2021; 117(5): 968-975.
SIMONNET A, et al. High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) Requiring Invasive Mechanical Ventilation. Obesity, 2020; 28(7): 1195–9.
TSANG HF, et al. An update on COVID-19 pandemic: the epidemiology, pathogenesis, prevention and treatment strategies. Expert Review of Anti-infective Therapy., 2021; 19(7): 877-88.
WANG B, et al. Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis. Aging (Albany NY), 2020; 12(7): 6049–57.
WU Z e MCGOOGAN JM. Characteristics of and Important Lessons from the Coronavirus Disease 2019 (COVID-19) Outbreak in China. JAMA, 2020; 323(13): 1239.
YANBIN DU, et al. Hypertension is a clinically important risk factor for critical illness and mortality in COVID-19: A meta-analysis. NMCD, 2021; 31(1): 745-755.
YANG J, et al. Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis. International Journal of Infectious Diseases, 2020; 94: 91–5.
ZHANG JJY, et al. Risk Factors for Severe Disease and Efficacy of Treatment in Patients Infected With COVID-19: A Systematic Review, Meta-Analysis, and Meta-Regression Analysis. Clinical Infectious Diseases, 2020; 71(16): 2199-206.
