Keywords
Lithium
Bipolar affective disorder
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Abstract
Objeticve: To investigate in the scientific literature whether there is a better treatment for Bipolar Affective Disorder (BAD) comparing the antipsychotics lithium and quetiapine, in addition to better understanding these drugs and their actions in that disease. Methods: Full articles, books and documents, clinical trials, meta-analyses, randomized controlled studies were selected from the PubMed database, which addressed the evidence of efficacy, side effects and adverse effects of lithium and/or quetiapine in the therapy of patients with bipolar disorder. affective disorder, published between 2018 and 2022. Results: Studies have shown that quetiapine and lithium are widely used in patients with Bipolar Affective Disorder (BAD), a condition that is difficult to manage and control in psychiatry. The main difficulty with these antipsychotics is the side effects, which are often responsible for discontinuing treatment. Final considerations: There was no consensus in the literature about which drug is superior to the treatment of bipolar affective disorder (BAD), whether lithium or quetiapine, both drugs are part of the treatment, presenting advantages and disadvantages in relation to the side effects of quetiapine. have a greater weight in non-adherence to treatment by patients.
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