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Keywords
Hypertension
Blood pressure
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Abstract
Objective: Complement the literature, summarize the subject and clarify the relation between Chronic Kidney Disease (CKD) and hypertension. Methods: This integrative review used ''PubMed'' and ''Scielo’' databases to search for the ''Renal Function'', ''Hypertension'', ''Kidney Function'', ''Renal Insufficiency, Chronic'' and ''Chronic Kidney Disease'' descriptors associated with Boolean operators, resulting in 1116 articles, in which 20 of them were chosen. Results: CKD has a high mortality rate due to its silent or nonspecific character. It is characterized by functional and/or structural kidney abnormalities for more than three months. The glomerular filtration rate is used for diagnosis and staging and, as main etiologies, hypertension and diabetes are the most common ones. However, there is no simple and reliable explanation for the direct physiopathogenesis. Antihypertensive drugs, glycemic control drugs and lipid modifiers are essential for progression-modifying therapy, although there are studies reporting that intensive pressure treatment and the use of hydralazine can worsen renal function. Final considerations: More emphasis on screening and early diagnosis is essential to improve the health of patients, especially those with comorbidities. Therefore, more studies are needed to elucidate its relation with hypertension, intensive pressure treatment and other associations.
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