Resumen
Objetivo: Evaluar los factores que aumentan y disminuyen los predictores de mortalidad en pacientes con shock séptico. Métodos: Las bases de datos utilizadas fueron la Biblioteca Nacional de Medicina, Biblioteca Virtual en Salud y Directorio de Revistas de Acceso Abierto. Los descriptores utilizados fueron: "Choque Séptico", "Hemodinámica" y "Microcirculación".Los criterios de inclusión fueron ensayos clínicos aleatorizados y no aleatorizados, estudios clínicos, acceso libre, en inglés, portugués y español, estudios de casos y controles, estudios de cohortes y el marco de tiempo de publicación de 2012 a 2022. Resultados: Se analizaron los factores que aumentan y disminuyen la mortalidad en pacientes con shock séptico, entre ellos se encuentran altas dosis de noreprinefrina, oxigenoterapia liberal, hipoperfusión tisular, densidad vascular perfundida, anomalía retiniana, moteado, persistencia de lactato, hipoperfusión sublingual, hipoxia en la piel, cambios microvasculares, dosis de dobutamina y propofol, estimulación eléctrica en la piel, el objetivo de presión arterial de oxígeno entre 70 y 100 mmHg y hemodafiltración intermitente prolongada de alto volumen. Consideraciones finales: Se observaron alteraciones clínicas de la macro y microcirculación, causadas por sepsis, que pueden ayudar en el diagnóstico temprano. Además, es de suma importancia identificar los predictores clínicos de mortalidad en estos pacientes para elaborar un plan terapéutico eficaz.
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