Palabras clave
Automedicación
Microbiota
Tracto gastrointestinal
Cómo citar
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Resumen
Objetivo: Destacar de forma clara y objetiva los impactos de la automedicación con antibióticos en la microbiota del tracto gastrointestinal. Métodos: Este artículo utilizó estudios aleatorizados, abiertos y multicéntricos con exposición de individuos a antibióticos y un grupo placebo con análisis fecal, estudios transversales y de screening con análisis del microbioma intestinal, mediante metagenómica de escopeta, de individuos que se sometieron a terapia antimicrobiana y un Estudio seccional, epidemiológico y cuantitativo con entrevistas y aplicación de cuestionarios sobre la automedicación y el uso y conocimiento de antibióticos en una población determinada. Resultados: Se observaron cambios en la microbiota intestinal y tratamientos contra infecciones, disbiosis, impactos en la respuesta inmune e inflamatoria del cuerpo, aumento de la resistencia de las bacterias y cambios en la estructura del microbioma. Consideraciones finales: Se concluye que la automedicación con antibióticos es predominante en la población observada y estudiada. Además, las consecuencias de este fenómeno reflejan una falta de comprensión sobre la autoadministración de antimicrobianos y sus efectos metabólicos.
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