Google Scholar | Citations: 958 | h-index: 12 i10-index: 19
Prescription of psychiatric drugs in pediatric patients: a literature review
PDF (Portuguese (Brazil))

Supplementary Files

Certificado (Portuguese (Brazil))

Keywords

Over prescribing
Psychotropic drugs
Childhood

How to Cite

Prescription of psychiatric drugs in pediatric patients: a literature review. (2022). Revista Eletrônica Acervo Médico, 2, e9382. https://doi.org/10.25248/reamed.e9382.2022

Copyright © | All rights reserved.

The journal holds the exclusive copyright for the publication of this article under the terms of Brazilian law 9610/98.

Partial reproduction
The use of parts of the texts, figures and questionnaire of the article is free, being mandatory the citation of the authors and journal.

Total reproduction
It is expressly prohibited and must be authorized by the journal.

Abstract

Objective: To analyze the pattern of prescriptions for psychotropic drugs in children, relating to age and gender. Thus, evaluating the existence or not of inadequate prescriptions. Methods: The methodological approach of this work proposes a compilation of bibliographic research with a qualitative approach and descriptive character through an integrative literature review in the National Library of Medicine, Virtual Health Library and Directory of Open Access Journals databases. The descriptors used were “over prescribing”, “psychotropic drugs” and “child”. Inclusion criteria were journal article articles, clinical trial, clinical trials, randomized or non-randomized, case-control studies, cohort study, open access, published in English, Portuguese, Spanish, between 2010 and 2021 and range aged from 2 to 18 years. Results: The psychopharmaceuticals presented are anxiolytics, antipsychotics, antidepressants, antieplectics and psychostimulants used to control externalizing and internalizing behaviors. Externalizing agents, in turn, are prevalent in boys, showing divergence of prescriptions and symptoms according to the ages and sex addressed. Final considerations: Thus, the prescription of psychotropic drugs is inadequate and indiscriminate in most cases, not respecting the minimum ages for prescription, diagnosis and indication of each drug and class.

PDF (Portuguese (Brazil))

References

ABBAS S, et al. Psychopharmacological Prescriptions in Children and Adolescents in Germany. Dtsch Arztebl Int., 2016; 113: 396-403.

AKRAM G. Profiling psychotropic discharge medication from a children’s psychiatric ward. Int J Clin Pharm, 2015; 37: 753–757.

BACHMANN CJ, et al. Antipsychotic prescription in children and adolescents: an analysis of data from a German statutory health insurance company from 2005 to 2012. Dtsch Arztebl Int., 2014; 111: 25-34.

BIEDERMAN J, STEINGARD R. Psicofarmacologia em niños y adolescentes: un manual para el clinico. Washington, DC: OPS, 1990.

BONNOT O, et al. Influência do status socioeconômico nas prescrições de antipsicóticos entre jovens na França. BMC Psychiatry, 2017; 17: 82.

CEBALLOS GY, et al. Perfil de utilização do serviço do Centro de Atenção Psicossocial da Criança e do Adolescente no Brasil: 2008 a 2012. Braz J Psychiatry, 2019; 41: 138-147

CHON MW, et al. Prescription Pattern of Antidepressants for Children and Adolescents in Korea Based on Nationwide Data. J Korean Med Sci, 2017; 32: 1694-1701.

CINTRA KC, et al. Abordagens farmacológicas em psicofármacos. Rev Inic Cient Ext., 2019.

COOK BL, et al. Examining psychotropic medication use among youth in the U.S. by race/ethnicity and psychological impairment. General hospital psychiatry, 2017; 45: 32-39.

CUDDY E, CURRIE J. Treatment of mental illness in American adolescents varies widely within and across areas. Proceedings of the National Academy of Sciences of the United States of America, 2020; 117(39): 24039-24046.

DIAS PF, et al. Contexto e consequências do uso de psicofármacos em crianças e adolescentes. Revista Educação em Saúde, 2020; 8:1

HARTZ I, et al. Psychotropic drug use among 0–17 year olds during 2004–2014: a nationwide prescription database study. BMC Psychiatry, 2016; 16: 12.

HELOISA HA. Princípios gerais do emprego de psicofármacos. Rev. Bras. Psiquiatr, 2000; 22: 40-41.

HSIA Y, et al. TEDDY Network of Excellence. Comparison of antiepileptic drug prescribing in children in three European countries. Epilepsia, 2010; 51: 789-96.

JACK RH, et al. Incidence and prevalence of primary care antidepressant prescribing in children and young people in England, 1998-2017: A population-based cohort study. PLoS medicine, 2020;17:7.

JOHN A, et al. Recent trends in primary-care antidepressant prescribing to children and young people: an e-cohort study. Psychol Med, 2016; 46: 3315-3327.

JOHN AL, et al. Recent trends in the incidence of anxiety and prescription of anxiolytics and hypnotics in children and young people: An e-cohort study, Journal of Affective Disorders, 2015; 183: 134-141.

MADDEN C, et al. Treating our youngest patients: psychotropic medications in early childhood. Mo Med, 2014; 111: 207-211.

MINISTÉRIO DA SAÚDE. Secretaria de Atenção à Saúde. Departamento de Atenção Básica. Cadernos de Atenção Básica: Saúde Mental. 2013. Disponível em: https://bvsms.saude.gov.br/bvs/publicacoes/cadernos_atencao_basica_34_saude_mental.pdf. Acessado 06 de jan de 2022.

MURRAY ML, et al. Pharmacological treatments prescribed to people with autism spectrum disorder (ASD) in primary health care. Psychopharmacology (Berl), 2014; 231: 1011-1021.

NEWLOVE-DELGADO T, et al. Prescribing for young people with attention deficit hyperactivity disorder in UK primary care: analysis of data from the Clinical Practice Research Datalink. ADHD Atten Def Hyp Disord, 2019; 11: 255–262.

NIELSEN ES, et al. Trends in Off-Label Prescribing of Sedatives, Hypnotics and Antidepressants between Children and Adolescents - A Danish, Estudo Nationwide Register ‐ Based. Basic Clin Pharmacol Toxicol, 20171; (20): 360-367.

OLASHORE A, et al. Prescribing pattern of psychotropic medications in child psychiatric practice in a mental referral hospital in Botswana. Pan Afr Med J., 2017; 26: 83.

OLFSON M, et al. Stimulant Treatment of Young People in the United States. J Child Adolesc Psychopharmacol, 2016; 26: 520-526.

OLIVEIRA JRF, et al. Descrição do consumo de psicofármacos na atenção primária à saúde de Ribeirão Preto, São Paulo, Brasil. Cadernos de Saúde Pública, 2021.

O'SULLIVAN K, et al. Benzodiazepine prescribing in children under 15 years of age receiving free medical care on the General Medical Services scheme in Ireland. BMJ Open, 2015; 5.

SALONER B, et al. Second-generation antipsychotic use among stimulant-using children, by organization of medicaid mental health. Psychiatr Serv., 2014; 65.

SIDORCHUK A, et al. Benzodiazepine prescribing for children, adolescents, and young adults from 2006 through 2013: A total population register-linkage study. PLoS Med, 2018; 15.

SILVA CM, et al. Medicalização da queixa escolar e o uso de psicofármacos como resposta à questões comportamentais. Estudos e Pesquisas em Psicologia, 2018; 18: 738-754.

SULTAN RS, et al. Antipsychotic Treatment Among Youths With Attention-Deficit/Hyperactivity. JAMA Netw Open., 2019;2(8):e1911650..

TSAI CY, et al. Psychotropic medications prescribing trends in adolescents: A nationwide population-based study in Taiwan, International Journal for Quality in Health Care, 2017; 29: 861–866.