Palavras-chave
Doença Renal Crônica
Diabetes tipo 2
Efeitos
Como Citar
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Resumo
Objetivo: Analisar os efeitos dos análogos de GLP-1 na progressão da doença renal crônica (DRC) em pacientes com diabetes tipo 2, seus benefícios e riscos associados ao seu uso. Métodos: Revisão bibliográfica integrativa na base de dados PubMed Central (PMC), através da estratégia de pesquisa: ((GLP-1RA) OR (Glucagon-like peptide-1 receptor agonists) OR (GLP-1)) AND ((Chronic Kidney Disease) OR (CKD)) no período de 2019 a 2024. Após a busca inicial, 585 estudos foram identificados, e submetidos a critérios de seleção. Após a aplicação de critérios de inclusão e exclusão, 18 artigos foram selecionados para compor este estudo. Resultados: Analisou-se o impacto dos análogos de GLP-1 na função renal e progressão da DRC em pacientes com diabetes tipo 2, explorando os mecanismos de proteção renal, avaliando riscos potenciais em diferentes estágios da doença. Considerações finais: Estudos sugerem redução da albuminúria e retardo na queda da Taxa de Filtração Glomerular (TFG), promovendo assim, um prognóstico mais favorável. O uso de análogos de GLP-1 em pacientes DRC é benéfico na proteção renal, entretanto, ainda requer atenção especial em estágios avançados da doença para evitar possíveis complicações.
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