Resumo
Objetivo: Descrever a relação entre dietas à base de plantas e a modulação da microbiota intestinal, destacando seus efeitos na diversificação microbiana, metabolismo e resposta imunológica. Métodos: Nesta revisão integrativa foi consultada a base de dados do PubMed para identificação e seleção de estudos publicados entre 2020 e 2025. Os descritores utilizados incluíram "plant-based diet" “and” "gut microbiota". Critérios de inclusão abrangeram estudos com delineamento experimental e revisões sistemáticas que avaliassem a influência das dietas à base de plantas na microbiota intestinal. Resultados: Foram incluídos 11 artigos que atenderam os critérios de inclusão e exclusão da revisão, demonstrando como a dieta à base de plantas pode influenciar a composição e funcionalidade do microbioma intestinal humano. Considerações finais: As dietas à base de plantas promovem um microbioma intestinal mais diversificado e funcional, associado a menores riscos de doenças inflamatórias e metabólicas. Entretanto devem haver mais pesquisas que elucidem os mecanismos envolvidos nessas mudanças.
Referências
ALCORTA A, et al. Foods for Plant-Based Diets: Challenges and Innovations. Foods, 2021; 10 (293): 1-23.
CHULUCK JBG, et al. A influência da microbiota intestinal na saúde humana: uma revisão de literatura. Brazilian Journal of Health Review, 2023; 6 (4): 1-15.
COSTA LCRC, et al. Alimentos plant-based: inovação na indústria de alimentos. Revista científica multidisciplinar, 2024; 5 (3): 1-13.
CHEN H, et al. Plant-based and planetary-health diets, environmental burden, and risk of mortality: a prospective cohort study of middle-aged and older adults in China. Lancet Planet Health, 2024; 8: e545–53.
CURADO RVC, et al. Microbiota intestinal e doenças digestivas: explorando as conexões para melhorar a saúde digestiva. Revista Ibero- Americana de Humanidades, Ciências e Educação, 2024; 10 (6): 1-8.
DIMBA NR, et al. Effectiveness of Prebiotics and Mediterranean and Plant-Based Diet on Gut Microbiota and Glycemic Control in Patients with Prediabetes or Type 2 Diabetes: A Systematic Review and Meta-Analysis. Nutrients, 2024; 16 (3272): 1-16.
DIXIT K, et al. Restoration of dysbiotic human gut microbiome for homeostasis. Life Sciences, 2021; (278): 1-12.
DJEKIC D, et al. Effects of a Vegetarian Diet on Cardiometabolic Risk Factors, Gut Microbiota, and Plasma Metabolome in Subjects With Ischemic Heart Disease: A Randomized, Crossover Study. J Am Heart Assoc, 2020; 9: e016518.
FEHER A, et al. A Comprehensive Review of the Benefits of and the Barriers to the Switch to a Plant-Based Diet. Sustainability, 2020; 12 (4136): 1-18.
ILLESCAS O, et al. Mediterranean Diet to Prevent the Development of Colon Diseases: A Meta-Analysis of Gut Microbiota Studies. Nutrients, 2021; 13 (2234): 1-21.
KAHLEOVA H, et al. Effects of a Low-Fat Vegan Diet on Gut Microbiota in Overweight Individuals and Relationships with Body Weight, Body Composition, and Insulin Sensitivity. A Randomized Clinical Trial. Nutrients, 2020; 12 (2917): 1-16.
KHAVANDEGAR A, et al. Adherence to the Mediterranean diet can beneficially affect the gut microbiota composition: a systematic review. BMC Medical Genomics, 2024; 17(91): 1-25.
KIMBLE R, et al. Effects of a mediterranean diet on the gut microbiota and microbial metabolites: A systematic review of randomized controlled trials and observational studies. Critical Reviews in Food Science and Nutrition, 2023; 63(27): 8698–8719.
KOHNERT E, et al. Changes in Gut Microbiota after a Four-Week Intervention with Vegan vs. Meat-Rich Diets in Healthy Participants: A Randomized Controlled Trial. Microorganisms, 2021; 9(727): 1-15.
LI W, et al. Plant-Based Diet Index and Metabolic Risk in Men: Exploring the Role of the Gut Microbiome. The Journal of Nutrition, 2021;151: 2780–2789.
LOSNO EA, et al. Vegan Diet and the Gut Microbiota Composition in Healthy Adults. Nutrients, 2021; 13 (2402): 1-14.
MERRA G, et al. Influence of Mediterranean Diet on Human Gut Microbiota. Nutrients, 2021; 13(7): 1-12.
MESLIER V, et al. Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake. Gut,
; 69: 1258–1268.
MONTESINO CA, et al. Akkermansia muciniphila, una bacteria contra la obesidad y su relación con la dieta. Revisión sistemática. MLSHNR, 2024; 3(1): 73-88.
NABHAN GCH, et al. Efeitos dos diferentes padrões alimentares sobre a microbiota intestinal. Brazilian Journal of Health Review, 2025; 8(3): 1-18.
PAGLIAI G, et al. Influence of a 3‐month low‐calorie Mediterranean diet compared to the vegetarian diet on human gut microbiota and SCFA: the CARDIVEG Study. European Journal of Nutrition, 2019: 1-14.
PAUL JK, et al. Unlocking the secrets of the human gut microbiota: Comprehensive review on its role in different diseases. World Journal of Gastroenterology, 2025; 31(5): 1-20.
SAKKAS H, et al. Nutritional Status and the Influence of the Vegan Diet on the Gut Microbiota and Human Health. Medicina, 2020; 56(88): 1-15.
SCHORR KA, et al. A plant-based diet index to study the relation between diet and disease risk among adults: a narrative review. The Journal of Nutrition, Health and Aging, 2024; 28: 1-13.
SEEL W, et al. Role of Dietary Fiber and Energy Intake on Gut Microbiome in Vegans, Vegetarians, and Flexitarians in Comparison to Omnivores—Insights from the Nutritional Evaluation (NuEva) Study. Nutrients, 2023; 15(1914): 1-22.
SIDHU SRK, et al. Effect of Plant-Based Diets on Gut Microbiota: A Systematic Review of Interventional Studies. Nutrients, 2023; 15(1510): 1-14.
SOUZA VM, et al. Modulação da microbiota intestinal a partir de padrões alimentares vegetarianos e o impacto em marcadores do sistema imune inflamação: Uma revisão de literatura. Dissertação (Bacharel em Nutrição) – Faculdade de ciências aplicadas. Universidade estadual de campinas, Limeira, 2021; 45 p.
STANFORD J, et al. Diversity Plant-Based Diet and Gut Microbiome, Plasma Metabolome, and Symptoms in Adults with CKD. Clinical Research, 2025; 20: 619–631.
TREFFLICH I, et al. Is a vegan or a vegetarian diet associated with the microbiota composition in the gut? Results of a new cross-sectional study and systematic review. Critical reviews in food science and nutrition, 2019; 1549-7852: 1-16.
VALOIS RM, et al. Alimentação baseada em vegetais para controle e prevenção de doenças crônicas não transmissíveis: uma revisão integrativa. Revista Ibero- Americana de Humanidades, Ciências e Educação, 2024; 10 (5): 1-22.
