Resumo
Objetivo: Comparar índice de Tobin e a relação e P0.1/MIP como fatores preditivos para o desmame da ventilação mecânica em pacientes adultos. Métodos: Revisão sistemática conduzida conforme os critérios do Cochrane Handbook, PRISMA e AMSTAR 2. Foram incluídos ensaios clínicos randomizados que utilizaram o Índice de Tobin e a razão P0.1/MIP como preditores de desmame. Dois revisores independentes realizaram a seleção dos estudos, análise de risco de viés (RoB 2) e avaliação da qualidade das evidências (GRADEpro GDT). Resultados: Apenas dois estudos preencheram os critérios, totalizando 217 pacientes. Apesar de o Índice de Tobin ser mais citado na literatura, não houve diferença significativa de acurácia entre os preditores. Ambos os estudos apresentaram alto risco de viés e baixa qualidade de evidência. Considerações finais: O Índice de Tobin e o P0.1/MIP são considerados ferramentas confiáveis para prever o desmame da VMI, mas nenhum demonstrou superioridade clara. Os desfechos de tempo de ventilação e mortalidade não foram adequadamente explorados nos estudos incluídos.
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