Resumo
Objetivo: Analisar a associação entre apneia obstrutiva do sono e hipertensão em adultos, avaliando a magnitude dessa relação e sua possível contribuição como fator independente no difícil controle da pressão arterial. Métodos: Trata-se de uma revisão integrativa da literatura realizada através das bases PubMED, Biblioteca Virtual em Saúde (BVS) e Periódico CAPES, usando os descritores: ”Sleep Apnea, Obstructive”, “Hypertension”, “Drug”, e obtendo o truncamento de pesquisa: (Sleep Apnea, Obstructive) AND (Hypertension) AND (Drug). Foram encontrados 2.857 artigos, filtrados conforme critérios de inclusão (idiomas português, inglês e espanhol; período de 2021 a 2026; artigos completos) e exclusão (artigos duplicados, resumos, fora do escopo). Resultados: A apneia obstrutiva do sono está fortemente associada ao desenvolvimento, manutenção e maior gravidade da hipertensão arterial, especialmente em casos mais avançados. Seus mecanismos envolvem hipóxia intermitente, ativação simpática, inflamação e disfunção endotelial, contribuindo para maior risco cardiovascular e resistência ao tratamento. Além disso, a identificação e o manejo integrado da AOS são fundamentais para melhorar o controle pressórico e reduzir desfechos adversos. Conclusão: A apneia obstrutiva do sono é um importante fator determinante e agravante da hipertensão arterial. Seu reconhecimento e manejo são essenciais para otimizar o controle pressórico e reduzir o risco cardiovascular.
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