Abstract
Objective: The aim of the present study was to conduct a systematic review of the effect of the drug Remdesivir in the treatment of COVID-19. Methods: Research was carried out on Pubmed and other search platforms using the following terms: “COVID-19” or “SARS-CoV-2”, “remdesivir” and “systematic review”. Results: Through the selection of 8 articles for inclusion in this systematic review, two of which were phase III clinical studies, randomized, double-blind and placebo-controlled. With all stages completed, they found Remdesivir effective. Between the two in vitro studies, one showed that the drug is effective in inhibiting the infection by the virus, while another complemented it by showing that this inhibition occurs precisely through the path for which Remdesivir is well known. Finally, successful treatment with Remdesivir was identified in the first case of COVID-19 in the United States. Final Considerations: Based on this systematic review, the use of Remdesivir is considered promising in the treatment of COVID-19. However, other clinical studies need to be carried out to prove its effectiveness and safety.