Abstract
Objective: To relate non-alcoholic fatty liver disease (NGAHD) and the risk of cirrhosis, and to renew and describe the scientific knowledge on the subject over the past five years. Bibliographic review: NASH is defined by the abnormal accumulation of fat in hepatocytes. It is considered a public health problem due to its high prevalence and possible progression to cirrhosis and/or hepatocellular carcinoma. Risk factors are differentiated into modifiable and non-modifiable, with obesity as the underlying disease for the development of NASH. They present various stages of progression, which include hepatic steatosis, Non-Alcoholic Steatohepatitis (NHEA), hepatic fibrosis, cirrhosis and hepatocellular carcinoma. NASHD presents associations with other comorbidities such as metabolic syndrome, type 2 diabetes mellitus (DMT2) and atherogenic dyslipidemia. Final considerations: NASH consists of the accumulation of fat in the hepatocytes of individuals who do not consume or consume less than 30g of alcohol per day, leading to a metabolic disorder, progressive and generally asymptomatic, resulting in late diagnosis and increasing the risk of developing cirrhosis and/or hepatocellular carcinoma.
