Keywords
Endocrine neoplasm type 1
Neuroendocrine tumors
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Abstract
Objective: To analyze the presence of ectopic parathyroid in patients with type I multiple endocrine neoplasia available in the scientific literature. Methods: This is an integrative review of the last ten years, carried out in six stages. Data collection took place according to the pre-established inclusion and exclusion criteria, on the virtual platforms: PubMed, SciELO, LILACS and VHL, with five studies being selected. Results: Most patients with MEN-1 showed evidence of primary hyperparathyroidism in adolescence, with reduced life expectancy. When this condition is persistent, as occurs in patients with less than four parotid glands, one should look for ectopic parathyroids. The most common ectopic locations were intrathyroidal parenchyma, thyrothymic duct pathway and thymus. The main glands absent in the presence of ectopia were the lower left and right, with the left slightly more prevalent. Therefore, mastery of clinical findings can contribute to early diagnosis, as well as a better therapeutic approach to the patient, minimizing morbidity and mortality. Final considerations: Therefore, a thorough approach is essential in patients with less than four parathyroid glands in the usual location, as this is a rare condition and may indicate the presence of ectopy of these glands.
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