Abstract
Objective: To review in the literature the current aspects of the use of Phyllanthus niruri (rock breaker) in the treatment of renal lithiasis. Methods: This is an integrative review, conducted through a literature review of publications that investigated the use of Phyllanthus niruri in the treatment of renal lithiasis, indexed to Pubmed, Scielo and Lilacs databases. Original articles with cross-sectional, case-control and cohort design were included, as well as review articles in English, Portuguese and Spanish, with no year of publication limit. Results: Of the 52 articles, 17.3% (n = 9) were included for full reading and discussion. The available results allowed us to verify the benefits of using P. niruri in the control of urolithiasis, its antispasmodic and antihyperalgesic actions, and its phytochemical compounds involved in its therapeutic action. Regarding toxicity, it was not observed with the use of teas and extracts, although it is contraindicated in pregnancy. Its pharmacological activity was positive, as well as its clinical and marketing results. Final considerations: It is concluded, therefore, that the “stone breaker” has clinical potential for therapeutic approach of renal lithiasis in humans.