Abstract
Objective: To present, describe and discuss the findings of the literature related to hepatitis B and Delta co-infection in the Amazon. Methods: Data were collected by literature review based on PRISMA, using the keywords Coinfection, HBV, Hepatitis B, Hepatitis D and Amazon, published in Scielo, Lilacs, MedLine and Pubmed. How to apply to include selected items and original online review articles in Portuguese, Spanish, and English in the last 5 years. As exclusion criteria, repetitive articles were specified, besides articles not relevant to the search of the descriptors. Results: We collected 30 scientific articles, in which 12 were within the exclusion requirements and 18 papers in the inclusion. Which point out that both viruses are mainly transmitted sexually. As for genetic variability, HBV has eight very characteristic genotypes. The clinic is variable, requiring HDV with presence of HBV for the course of the disease. Pegylated interferon is the best therapeutic choice. In addition, new drugs are being followed by more affordable and effective treatment. Conclusion: The Brazilian literature on hepatitis B and D virus co-infection receives better evidence studies, highlighting the need for further research.
Key words: Coinfection, HBV/HDV, Hepatitis B, Hepatitis D.