Keywords
Glands
Neoplasms
How to Cite
Copyright © | All rights reserved.
The journal holds the exclusive copyright for the publication of this article under the terms of Brazilian law 9610/98.
Partial reproduction
The use of parts of the texts, figures and questionnaire of the article is free, being mandatory the citation of the authors and journal.
Total reproduction
It is expressly prohibited and must be authorized by the journal.
Abstract
Objective: Characterize the clinical and epidemiological behavior of Mucoepidermoid Carcinoma (MEC) in salivary glands over a 15-year period. Methods: The study is based on retrospective data from the Cancer Hospital Information and Records System (SisRHC) regarding MEC. Results: The results were obtained from the tabulation of 587 cases. Based on age group information, females were the most affected (55.03%). Individuals in the fourth decade of life, between 40 and 49 years old, represented the highest number of cases (17.72%). Regarding patients' race/ethnicity, there was a higher frequency of cases in individuals with a mixed-race background (72.74%). In terms of education level, it was observed that 27.26% of cases occurred in individuals with incomplete primary education. Conclusion: It was possible to conclude that, in the Brazilian Northeast, mucoepidermoid carcinoma showed a preference for the female gender, with an increase in cases starting from the third decade of life and remaining high until the sixth decade. There was little association of cases with a history of alcohol, tobacco, or family cancer. Additionally, it was observed that, after 1 year of treatment, the majority of cases remained stable, as well as a reduction in cases in the year 2020.
References
ALOUA R, et al. Mucoepidermoid carcinoma of the retromolar trigone in an elderly female: A case report. Annals of Medicine and Surgery, 2021; 67: 102487.
ARAUJO SEA, et al. Impact of COVID-19 pandemic on care of oncological patients: experience of a cancer center in a Latin American pandemic epicenter. Einstein, 2021; eAO6282–2.
CARTAXO AC, et al. Conhecimento de trabalhadores rurais de um município do nordeste brasileiro acerca da prevenção e diagnóstico precoce do câncer de boca. Revista Ciência Plural, 2017; 3(1): 51–62.
CHAN SA, et al. Mucoepidermoid carcinoma of the parotid gland: Twenty‐year experience in treatment and outcomes. Head & Neck, 2021; 43(9): 2663-2671.
CHOI S, et al. Molecular mechanism underlying the apoptotic modulation by ethanol extract of Pseudolarix kaempferi in mucoepidermoid carcinoma of the salivary glands. Cancer Cell International, 2021; 21(1): 1-12.
DE SOUZA LB, et al. Immunoexpression of GLUT-1 and angiogenic index in pleomorphic adenomas, adenoid cystic carcinomas, and mucoepidermoid carcinomas of the salivary glands. European Archives of Oto-Rhino-Laryngology, 2017; 274(6): 2549–56.
DEVARAJU R, et al. Mucoepidermoid carcinoma. Case Reports, 2014; bcr2013202776.
DOMINGUEZ-MEDINA DA, et al. A radiolucent lesion of the jaw as a presentation form of a mucoepidermoid carcinoma of the oral cavity. Journal of the Korean Association of Oral and Maxillofacial Surgeons, 2021; 47(3): 229–32.
FORD PJ e RICH AM. Tobacco Use and Oral Health. Addiction, 2021; 116(12): 3531-3540.
GANIMEZ JET. Carcinoma Mucoepidermoide, Revisión de la Literatura: Reporte de un caso. Acta Odontológica Venezolana, 2002; 40(1): 43-46.
GOMES DQC, et al. Mucoepidermoid carcinoma of the retromolar region: report of a clinical case. RGO - Revista Gaúcha de Odontologia, 2015; 63(1): 103–8.
GONÇALO RIC, et al. Mucoepidermoid carcinoma of the retromolar region: case report. Jornal Brasileiro de Patologia e Medicina Laboratorial, 2020; 56.
GOTOH S, et al. Mucoepidermoid carcinoma of the anterior lingual salivary gland: A rare case report. Molecular and Clinical Oncology, 2021; 14: 16(1).
GRANADOS RH, et al. Carcinoma mucoepidermoide. Revista de la Asociación Dental Mexicana, 2010; 67(4): 181-184.
HARADA F, et al. Intraosseous clear cell mucoepidermoid carcinoma in the maxilla: A case report and review of literature. Clinical Case Reports, 2021; 9(7).
JANET-OFELIA GC, et al. Mucoepidermoid Carcinoma of the Salivary Glands: Survival and Prognostic Factors. Journal of Maxillofacial and Oral Surgery, 2016; 16(4): 431–7.
JEERGAL PA, et al. Mucoepidermoid carcinoma: A retrospective clinicopathologic study of 25 cases. Journal of Oral and Maxillofacial Pathology: JOMF, 2021; 25(3): 490–3.
KANSOU KA, et al. Origens do carcinoma mucoepidermoide central: revisão sistemática. Revista de Medicina, 2021; 100(1): 41-48.
KESHANI F, et al. Estrogen receptor α expression in different stages of salivary gland mucoepidermoid carcinoma. Dental Research Journal, 2022; 19.
LEE DH, et al. Sclerosing mucoepidermoid carcinoma of the sublingual gland. European annals of otorhinolaryngology, head and neck diseases, 2017; 134(5): 355-356.
LEMOS JUNIOR CA, et al. Câncer de boca baseado em evidências científicas. Revista da Associação Paulista de Cirurgiões Dentistas, 2013; 67(3): 178–86.
MONTERO PH e PATEL SG. Cancer of the Oral Cavity. Surgical Oncology Clinics of North America, 2015; 24(3): 491–508.
MORAIS EF, et al. Intraosseous maxillary mucoepidermoid carcinoma: a rare case report. Jornal Brasileiro de Patologia e Medicina Laboratorial, 2019; 55(5): 540-549.
NASCIMENTO CC, et al. Desafios e Recomendações à Atenção Oncológica durante a Pandemia da Covid-19. Revista Brasileira de Cancerologia, 2020; 66: e1241.
PIRES FR, et al. Carcinoma mucoepidermóide de cabeça e pescoço: estudo clínico-patológico de 173 casos. Revista Brasileira de Otorrinolaringologia, 2002; 68(5): 679-684.
REM J e SHIELD KD. Alcohol Use and Cancer in the European Union. Eur Addict Res, 2021; 27(1): 1-8.
RENY DC, et al. Predictors of Nodal Metastasis in Mucoepidermoid Carcinoma of the Oral Cavity and Oropharynx, 2020; 82(6): 327–34.
ROBINSON L, et al. Expression of Mucins in Salivary Gland Mucoepidermoid Carcinoma. Head and Neck Pathology, 2020; 15(2): 491–502.
RODRIGUES AAN, et al. Carcinoma mucoepidermoide: caso raro em paciente jovem. Revista da Faculdade de Ciências Médicas de Sorocaba, 2016; 18(3): 173–6.
SANTOS TS, et al. Carcinoma mucoepidermóide no palato: relato de caso. Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial, 2012; 53(1): 29–33.
SANTOS GL, et al. Fumo e álcool como fatores de risco para o câncer bucal. Odontologia Clínico-Científica (Online), 2010; 9(2): 131– 3.
SHARMA S, et al. Mucoepidermoid carcinoma-A common neoplasm at an unusual site, mimicking a benign cyst on cytology: Diagnostic pitfall!. Journal of Oral and Maxillofacial Pathology, 2022. 26: S30.
SILVA DC, et al. Metilação de DNA e proliferação em carcinoma mucoepidermóide: estudo in vitro. Brazilian Oral Research. 2018; 32: 221.
TRATTNER BA, et al. Mucoepidermoid Carcinoma Mimicking a Lesion of Endodontic Origin. Journal of Endodontics, 2018; 44(8): 1303–7.
VAIDYA K, et al. Central mucoepidermoid carcinoma associated with impacted tooth mimicking as dentigerous cyst. Oral oncology, 2021; 121: 105333.
VERGARA GV, et al. Desafío diagnóstico y terapéutico de carcinoma mucoepidermoide palatino: reporte de un caso. Revista de otorrinolaringología y cirugía de cabeza y cuello, 2021; 81(2): 226–31.
WANG Y, et al. A Population‐Based Analysis of Mucoepidermoid Carcinoma of the Oral Cavity. The Laryngoscope, 2021; 131(3): E857-E863.
ZHANG HY, et al.Mucoepidermoid carcinoma in the infratemporal fossa: A case report. World Journal of Clinical Cases, 2020; 8(14): 3090.
ZINI M, et al. Carcinoma mucoepidermoide em palato: relato de caso. Revista de Cirurgia e Traumatologia Buco- maxilo-facial, 2010; 10(1): 57–62.