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The use and non-use of medications during pregnancy: potential risk factors for the development of congenital malformations
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Keywords

Pregnant Women
Drug Compliance
Teratogens
Congenital Abnormalities
Drug-Induced Abnormalities

How to Cite

The use and non-use of medications during pregnancy: potential risk factors for the development of congenital malformations. (2024). Electronic Journal Collection Health, 24(8), e15221. https://doi.org/10.25248/reas.e15221.2024

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Abstract

Objective: To know the behavior of women in the state of Roraima regarding the use of medications during pregnancy. Methods: Survey using an epidemiological form. Results: Of the total of 158 participants, 37.3% bear children with congenital malformations and 62.7% did not. The mean age (p=0.0380) together with low family income (p=0.0259) between the groups was statistically significant, with women aged between 13 and 25 years old (p=0.0006) are at greater risk of having children with congenital defects. Furthermore, the lack of maternal compliance to drug treatment (p=0.0260; OR: 2.727; CI: 1.156-6.434) was also associated with the development of these abnormalities. In addition, the use of analgesics (p=0.0577; OR: 3.725; CI: 1.070-12.975) and antibiotics (p=0.0588; OR: 2.259; CI: 1.009-5.057) before and during the gestational period, seems to favor the appearance of congenital malformations. Conclusion: Women in the age group of 13 to 25 years old, with income less than or equal to the minimum wage and who do not use medications prescribed during pregnancy, are associated to the development of children with congenital malformations. In addition, the use of analgesics and antibiotics before and during the gestational period seems to favor the appearance of these abnormalities.

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