Keywords
COVID-19
HIV
Co-infection
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Abstract
Objective: To analyze in the scientific literature clinical consequences resulting from SARS-CoV-2 co-infection in people living with the human immunodeficiency virus (PLHIV). Literature Review: COVID-19 has a range of clinical manifestations, with symptoms similar to those of the flu (fever, cough and lethargy). It was found that the presence of comorbidities contributed to the severity of the infection, affecting the individual's immune system. Therefore, it is feasible to assume that people with other health problems that affect immunity, such as HIV infection, could develop more serious cases. The existence of clinical consequences resulting from COVID-19 co-infection in PLHIV was analyzed. Overall, the data suggest that PLHIV infected by COVID-19 do not have a clinical condition that requires greater interventions than HIV-seronegative individuals, showing that not the presence of HIV, but immunocompromise can contribute to the most severe cases. Final considerations: New studies are needed to investigate co-infection between HIV and COVID-19 with larger samples and that are capable of tracking the mechanisms of interaction between these viruses in co-infection.
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