Keywords
Antimicrobials
Antimicrobial resistance
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Abstract
Objective: To analyze the impact of rampant antibiotic use during the pandemic and its relation to bacterial resistance. Methods: This is an integrative review with a qualitative approach, examining scientific articles from Google Scholar, EbscoHost, PubMed, and SciELO, published between 2019 and 2023, in languages that include English, Portuguese, and Spanish. Results: Lack of knowledge about antibiotics and the dissemination of inadequate information led to a quest for quick and improvised treatment solutions. This phenomenon contributed to the rise in antimicrobial resistance, mainly in low- and middle-income countries with fewer resources, impacting the global economy by increasing medication sales while compromising public health. Hence, discussions focused on crisis management, emphasizing the urgent need to expand research into new antibiotics, improve infection prevention methods, and explore COVID-19 treatment alternatives. Final considerations: It can be considered that the pandemic escalated antimicrobial usage and its effect on bacterial resistance, vital for understanding public health challenges and guiding future health policies.
References
CALDAS AF, et al. Resistência bacteriana decorrente do uso indiscriminado de antibióticos. Scire Salutis, 2022; 12(1): 1-7.
CHAGAS AP e LIMA VP. Rápida inserção e disseminação da resistência bacteriana em uma unidade covid e o impacto no tratamento antimicrobiano empírico de pacientes com bacteremia. The Brazilian journal of infectious diseases, 2022; 26(2): 107-108.
CRISTALDO YC, et al. O uso indiscriminado de antibióticos e sua relação com a resistência bacteriana. Tópicos especiais em ciências da saúde: teoria, métodos e práticas, 2022; 5 (1): 117-128.
DA SILVA KR, et al. Implicações do uso de antibióticos durante a pandemia de COVID-19. Reaserch, Society and Development, 2021; 10(7): 1-9.
DOS SANTOS ML, et al. Aumento do consumo de antibióticos em ambiente hospitalar durante a pandemia de Covid-19. Brazilian Journal of Health Review, 2023; 6(1): 2341-2350.
GAUTRET P, et al. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. International Journal of Antimicrobial Agents, 2020; 56(1): 1-6.
GHOSHA S, et al. Antimicrobial Resistance Threats in the emerging COVID-19 pandemic: Where do we stand? Jornal de Infecção e Saúde Pública, 2021; 14(1): 556-560.
GUIMARÃES DO, et al. Antibióticos: importância terapêutica e perspectivas para a descoberta e desenvolvimento de novos agentes. Química nova, 2010; 33(3): 667-679.
HUEMER M, et al. Antibiotic resistance and persistence Implications for human health and treatment perspectives. EMBO reports, 2020; 21(12): 1-24.
MELO JRR, et al. Automedicação e uso indiscriminado de medicamentos durante a pandemia da COVID-19. Cadernos de Saúde Pública, 2021; 37(4): 1-5.
MIRANDA C, et al. Implications of antibiotic use during the COVID-19 pandemic: present and future. Journal of Antimicrobial Chemotherapy, 2020; 75(12): 3413-3416.
OLIVEIRA LJ, et al. Aumento do uso de antibióticos durante a pandemia de COVID-19 em cidade do interior de Minas Gerais. RECIMA21, 2021; 2(8): 1-8.
OLIVEIRA M, et al. Resistência bacteriana pelo uso indiscriminado de antibióticos: uma questão de saúde pública. Revista Ibero-Americana de Humanidade, Ciências e Educação, 2020; 6(11): 183-201.
OMS. Estratégia para contenção de resistência microbiana. 2022. Disponível em: https://www.who.int/publications/i/item/9789240062702. Acesso em: 15 de setembro de 2023.
PAGE MJ, et al. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. Bmj. 2021; 372(160): 1-36.
PAULA HSC, et al. An overview on the current available treatment for COVID-19 and the impact of antibiotic administration during the pandemic. Revista Brasileira de Pesquisa Médica e biológica. 2022; 55(1):1-12.
PULIA M, et al. COVID-19: An Emerging Threat to Antibiotic Stewardship in the Emergency Department. Western Journal of Emergency Medicine, 2020: 21(5): 1283-1286.
RAWSON TM, et al. Bacterial and fungal co-infection in individuals with coronavirus: A rapid review to support COVID-19 antimicrobial prescribing. Clinical Infectious Diseases. 2020; 71(9): 2459-2468.
RIZVI SGI e AHAMMAD XZ. COVID-19 and antimicrobial resistance: a crossover study. Ciência do Meio Ambiente, 2021; 807(2): 1-12.
SOUZA JF, et al. Resistência bacteriana aos antibióticos. Revista JRG de Estudos Acadêmicos, 2022; 5(10): 281–293.
SULIS G, et al. antimicrobial resistance in low- and middle-income countries: current status and future directions, Expert Review of Anti-infective Therapy, 2022; 20(2): 147-160.
SULIS G, et al. Antibiotic prescription practices in primary care in low- and middle-income countries: A systematic review and meta-analysis. Plos Medicine, 2020; 17(06): 1-20.
TEIXEIRA AR, et al. Resistência bacteriana relacionada ao uso indiscriminado de antibióticos. Revista Saúde em Foco, 2019; 11(1): 853-857.
UKUHOR J. The interrelationships between antimicrobial resistance, COVID-19, past, and future pandemics. Journal Infect Public Health, 2021; 14(1): 53-60.
VELLANO PO e DE PAIVA MJM. O uso de antimicrobiano na COVID-19 e as infecções: o que sabemos. Research, Society and Development, 2020; 9(9): 1-18.
WILSON LA, et al. Lessons learned from Covid-19 for the post-antibiotic future Globalização e Saúde, 2020; 94(1): 1-3.