Abstract
Objective: To describe the case of a child with Chronic Osteomyelitis in the Mandible, a rare disease that presents with periods of exacerbation and requires long treatment, in addition to being a diagnostic challenge for pediatricians and pediatric dentists. The condition may present with facial asymmetry, pain, physical and psychological disorders to the patient, especially in childhood. Case details: She required prolonged use of antibiotics, as well as surgical interventions, until the final diagnosis of Diffuse Sclerosing Osteomyelitis (DSO), in association with a Chronic Tendoperiostitis. With multi-professional care, which is still in progress, the patient is clinically stable with conservative treatment based on painkillers and anti-inflammatories. Final considerations: The diagnosis and treatment of chronic osteomyelitis of the jaw are challenging for healthcare professionals. This paper reports on a successful experience in which the patient had significant clinical improvement and is being followed up to control the disease.
References
AKGÜL H, et al. Garre's Osteomyelitis of the Mandible Caused by Infected Tooth. Case Rep Dent, 2018; 1409539.
ANDRE CV, et al. Osteomyelitis of the jaws: A retrospective series of 40 patients. J Stomatol Oral Maxillofac Surg, 2017; 261-264.
BELLI E, et al. Sclerosing Osteomyelitis of Garré Periostitis Ossificans. Journal of Craniofacial Surgery, 2002; 13 (6): 765-8.
CAMISON L, et al. Chronic Recurrent Multifocal Osteomyelitis of the Mandible: A Diagnostic Challenge. Plast Reconstr Surg, 2018; 186-192.
FERNANDES VC. Osteomielite crônica com periostite proliferativa. Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, 2012.
FUKUDA M, et al. Periostitis ossificans arising in the mandibular bone of young patient: Report of an unusual case and review of the literature. J Oral Maxillofac Surg, 2017; 1834.e1-1834: e8.
HAEFFS TH, et al. Acute and Chronic Suppurative Osteomyelitis of the Jaws: A 10-Year Review and Assessment of Treatment Outcome. J Oral Maxillofac Surg, 2018; 2551-2558.
HOFMAN SR, et al. ChronicRecurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment. Curr Osteoporos Rep, 2017; 542-554.
HUH WW, et al. Osteosarcoma of the jaw in children and young adults. Head Neck, 2012; 34(7): 981-984.
JAIN M, et al. Garre's Sclerosing Chronic Osteomyelitis of Femur in an Adolescent. J Orthop Case Rep, 2021; (12): 15-18.
KOGSTAD MD, et al. Hematogeneous osteomyelitis in children: management. Up to Date, 2023; 8(2): 175-81.
KORYLLOU A, et al. Chronic Nonbacterial Osteomyelitis in Children. Children (Basel), 2021; (7): 55.
KUANKUAN DDS, et al. Is Operative Management Effective for Non-Bacterial Diffuse Sclerosing Osteomyelitis of the Mandible. J Oral Maxillofac Surg, 2021; (11): 2292-2298.
KUDVA A, et al. Chronic recurrent osteomyelitis: A surgeon's enigma. J Oral Pathol Med, 2019; (2): 180-184
LIUD, et al. Chronic osteomyelitis with proliferative periostitis of the mandibular body: report of a case and review of the literature. Ann R Coll Surg Engl, 2019; (5): 328-332.
MA L, et al. Clinical characteristics and outcomes of chronic nonbacterial osteomyelitis in children: a multicenter case series. Pediatr Rheumatol Online J, 2022; 20(1).
MOARES FB, et al. Osteomielite esclerosante de Garrè: relato de caso. Revista Brasileira de Ortopedia, 2014; 401-404.
NEVILLE BW, et al. Patologia Oral e Maxilofacial. 4ª edição. Rio de Janeiro: Elsevier; 2016.
OBEL G, et al. Juvenile mandibular chronico steomyelitis: 3 cases and a literature review. J Oral Maxillofac Surg, 2013; (2): 305-309.
PACINO GA, et al. Jawbone fibrous dysplasia: retrospective evaluation in a cases series surgically treated and short review of the literature. Acta Biomed, 2020; e2021018.2020 Acta Biomed. 2020; 92(1): e2021018.
RODRIGUES MF, et al. Osteomielite crônica mandibular em pacientes pediátricos. Arch Health Invest, 2020; (1): 55-59.
SCHWARZKOPF E, et al. Chronic recurrent multifocal osteomyelitis-case report of two patient sand review of literature. Int J Clin Rheumtol, 2019; (1): 24-30.
SHANMUGA JS, et al. Garré's Sclerosing Osteomyelitis with Perimandibular Soft Tissue Inflammation and Fistula, Indian J Radiol Imaging, 2022; (4): 1016-1018.
SHAW SE, et al. Non-Odontogenic Tumors of the Jaws. StatPearls Treasure Island (FL), 2023.
TAIHI I, RADOI L. Chronic non-suppurative mandibular osteomyelitis with proliferative periostitis: A review. Quintessence Int, 2018; (3): 219-226.
VAN DE MEENT MM, et al. Conservative treatment of children with chronic diffuse sclerosing osteomyelitis/tendoperiostitis of the mandible. J Craniomaxillofac Surg, 2017; (12): 1938-1943.
VAN DE MEENT MM, et al. Outcome of different treatments for chronic diffuse sclerosing osteomyelitis of the mandible: a systematic review of published papers. Br J Oral Maxillofac Surg, 2020; (4):385-395.
WALTER N, et al. The Epidemiology of Osteomyelitis in Children. Children (Basel), 2021; (11):1000.
ZHAO DY, FERGUSON PJ. Chronic nonbacterial osteomyelitis (CNO) and chronic recurrent multifocal osteomyelitis (CRMO). Pediatr Clin North Am, 2018; (4): 783-800.
ZIMMERMANN C, et al. Diagnostic Challenge and Clinical Management of Juvenile Mandibular Chronic Osteomyelitis. Head NeckPathol, 2020; (3): 842-846.
