Keywords
Adverse effects
Drug therapy
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Abstract
Objective: To identify the screening tools used in the literature as screeners for adverse drug reactions in the intensive care patients and the evidence that supports the routine use of these tools. Methods: This is a systematic review of the literature, based on primary studies related to the topic, published in PubMed, Scopus, Web of Science, Lilacs and EMBASE, and in more common journals that publish on patient safety. Results: The work included 4 primary studies, the results show the trackers as an effective method for identifying ADRs in critical patients, and suggest that an ideal model is one that includes more efficient alerts to identify a greater number of possible harms to the patient, compounds due to prescription or abrupt suspension of certain medications, changes in laboratory tests and specific events during the period of hospitalization, which must be subject to modifications to adapt to the practice or culture of the institutions. Final considerations: The scarcity of studies points to the need for more research in this area so that the use of these tools can be better understood and reproduced.
References
BHISE V, et al. An electronic trigger based on care escalation to identify preventable adverse events in hospitalised patients. BMJ Quality & Safety. 2017; 27(3): 241–6.
BRENNER S, et al. Signal and noise: applying a laboratory trigger tool to identify adverse drug events among primary care patients. BMJ Quality & Safety. 2012; 21(8): 670–5.
BUCKLEY MS, et al. Trigger alerts associated with laboratory abnormalities on identifying potentially preventable adverse drug events in the intensive care unit and general ward. Therapeutic Advances in Drug Safety. 2018; 9(4): 207-217.
COLEMAN JJ e PONTEFRACT SK. Adverse drug reactions. Clin Med (Lond). 2016; 16(5): 481-485.
DIPOTO JP, et al. Evaluation of an Automated Surveillance System Using Trigger Alerts to Prevent Adverse Drug Events in the Intensive Care Unit and General Ward. Drug Safety. 2015; 38(3): 311–7.
GRIFFIN FA e RESAR RK. IHI Global Trigger Tool for Measuring Adverse Events (Second Edition). IHI Innovation Series white paper. Cambridge, Massachusetts: Institute for Healthcare Improvement; 2009. Disponível em: www.IHI.org. Acessado em: 25 de janeiro de 2022.
HIBBERT PD, et al. The application of the Global Trigger Tool: a systematic review. International Journal for Quality in Health Care. 2016.
HOUGLAND P, et al. Performance of International Classification of Diseases, 9th Revision, Clinical Modification Codes as an Adverse Drug Event Surveillance System. Medical Care [Internet]. 2006; 44(7): 629–36. Disponível em: https ://www.jstor.org/stable/40221330. Acessado em: 2 de julho de 2023.
JBI. JBI Manual for Evidence Synthesis. Aromataris E, Munn Z, editors. JBI; 2020.
KANE-GILL SL, et al. Use of Text Searching for Trigger Words in Medical Records to Identify Adverse Drug Reactions within an Intensive Care Unit Discharge Summary. Appl Clin Inform. 2016; 7(3): 660-71.
KHAN LM, et al. Detection of adverse drug reactions by medication antidote signals and comparison of their sensitivity with common methods of ADR detection. Saudi Pharmaceutical Journal. 2015; 23(5): 515–22.
LOPEZ-GONZALEZ E, et al. Determinants of under-reporting of adverse drug reactions: a systematic review. Drug Saf. 2009; 32(1): 19-31.
MARTINS RR, et al. Trigger tools are as effective as non-targeted chart review for adverse drug event detection in intensive care units. Saudi Pharmaceutical Journal [Internet]. 2018 Dec [cited 2020 Jan 30];26(8):1155–61. Disponível em: https ://www.sciencedirect.com/science/article/pii/ S1319016418301427. Acessado em: 25 de janeiro de 2022.
MOLINA FJ, et al. Adverse events in critical care: Search and active detection through the Trigger Tool. World Journal of Critical Care Medicine. 2018; 7(1): 9–15.
MUNN Z, et al. Methodological guidance for systematic reviews of observational epidemiological studies reporting prevalence and cumulative incidence data. International Journal of Evidence-Based Healthcare. 2015 Sep; 13(3): 147–53.
NEBEKER J, et al. Considering sensitivity and positive predictive value in comparing the performance of triggers systems for iatrogenic adverse events. Abstract presented at the Agency for Healthcare Research and Quality Annual Conference. Bethesda, MD, September 2009.
PIERDEVARA L, et al. An experience with the Global Trigger Tool for the study of adverse events in a medical ward. Revista de Enfermagem Referência. IV Série. 2016; 97-106.
PIERDEVARA L, et al. Trigger Tool na Segurança do Doente: Uma Revisão Sistemática de Literatura. Portuguese Journal of Public Health, 2017; 35(2): 69–76.
RATZ Y, et al. The Importance of the Pharmacist in Reporting Adverse Drug Reactions in the Emergency Department. The Journal of Clinical Pharmacology. 2010; 50(10): 1217–21.
SHAMSEER L, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ [Internet]. 201; 349(1): 7647–7. Disponível em: https ://www.bmj.com/content/349/bmj.g7647. Acessado em: 25 de janeiro de 2022.
SHEIKH A, et al. The third global patient safety challenge: tackling medication-related harm. Bulletin of the World Health Organization [Internet]. 2017 Aug 1;95(8):546–6A. Disponível em: https ://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537758/. Acessado em: 25 de janeiro de 2022.
TUFANARU C, et al. Chapter 3: Systematic Reviews of Effectiveness. JBI Manual for Evidence Synthesis. 2020.
WELLS G, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality if nonrandomized studies in meta-analyses. Ottawa Hospital Research Institute [Internet]. www.ohri.ca. 2021. Disponível em: https ://www.ohri.ca/programs/clinical_epidemiology/oxford.asp. Acessado em: 7 de março de 2022.
ZAUGG H, et al. Mendeley: Creating communities of scholarly inquiry through research collaboration. TechTrends, 2011; 55(1): p.32-36.