Keywords
Elderly health
List of potentially inappropriate medications
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Abstract
Objective: To evaluate the prevalence of the use of potentially inappropriate medications (PIM) in hospitalized elderly people, polypharmacy and associated risk factors, in addition to identifying possible Medication-Related Problems (DRP). Methods: This is a descriptive, retrospective and quantitative cross-sectional study, conducted with 86 individuals, aged ≥ 60 years, carried out from July to October 2023 at the Medical Clinic Unit (UCM) of the University Hospital. The Beers Criteria (2019) was used to evaluate MPI, the PRM assessment was carried out according to Strand. Pearson's Chi Square test was used to determine associations (p<0.05) between sex, DRP and polypharmacy. Results: A total of 88.3% of patients had MPI when prescribed from admission to discharge, the most prescribed were proton pump inhibitors (51.11%) and antipsychotics (16.29%), 27 patients had one or more DRPs during hospitalization. No statistical significance was observed for the variable polypharmacy and gender (p=0.859) and presence of DRP (p=0.308). Conclusion: Due to the high prevalence of PIM that should be avoided in the elderly and due to polypharmacy, health education is important to avoid problems and health problems resulting from the use of inappropriate medications. The study should be expanded on the relationship between DRPs and polypharmacy in line with more robust studies.
References
ALHARBI SA, et al. Polypharmacy and inappropriate prescribing in elderly patients: a retrospective study at Buriadah Central Hospital, Saudi Arabia. Eur Rev Med Pharmacol Sci. 2022; 26(9): 3325-3333.
ALMEIDA TA, et al. Factors associated with the use of potentially inappropriate medications by older adults in primary health care: An analysis comparing AGS Beers, EU (7)-PIM List, and Brazilian Consensus PIM criteria.
Research in Social and Administrative Pharmacy. 2019; 15(4): 370–7.
BANCO MUNDIAL. Dados abertos do banco mundial, 2022.
BY THE 2019 AMERICAN GERIATRICS SOCIETY BEERS CRITERIA® UPDATE EXPERT PANEL. American Geriatrics Society 2019 updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults: 2019 Ags beers criteria® update expert panel. J Am Geriatr Soc. 2019; 67(4): 674–94.
BY THE 2023 AMERICAN GERIATRICS SOCIETY BEERS CRITERIA® UPDATE EXPERT PANEL. American Geriatrics Society 2023 updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2023; 71(7): 2052–81.
CANIO WC. Polypharmacy in older adults. Clin Geriatr Med. 2022; 38(4): 621–5.
CLARK CM, et al. Transitions of Care: Strategies for Medication Optimization and Deprescribing in Older Adults. J Gerontol Nurs. 2023; 49(12): 5-10.
DAGNEW SB, et al. Clinical pharmacist intervention on drug-related problems among elderly patients admitted to medical wards of Northwest Ethiopia comprehensive specialized hospitals: A multicenter prospective, observational study. Biomed Res Int [Internet]. 2022; 1–11.
FU JL e PERLOFF MD. Pharmacotherapy for spine-related pain in older adults. Drugs Aging. 2022; 39(7): 523– 50.
GONÇALVES KS, et al. Factors associated with potential drug interactions in hospitalized elderly people with acute heart failure. J. Health NPEPS. 2023; 8(2).
KING E, et al. Potentially Inappropriate Medication Use among Underserved Older Latino Adults. J Clin Med. 2023; 12(9): 3067
LI M, et al. Prevalence and clinical implications of polypharmacy and potentially inappropriate medication in elderly patients with heart failure: results of six months' follow-up. J Geriatr Cardiol. 2023; 20(7): 495-508.
MA W, et al. Potentially inappropriate medication and frailty in older adults: A systematic review and meta- analysis. Arch Gerontol Geriatr. 2023; 114: 105087.
MCCARTHY C, et al. Medication changes and potentially inappropriate prescribing in older patients with significant polypharmacy. Int J Clin Pharm. 2023; 45(1): 191–200.
PEREIRA VG, et al. Fatores associados às doenças crônicas não transmissíveis na população idosa. 2023; 23(6): 12719.
PRAXEDES MFDS, et al . Prescrição de medicamentos potencialmente inapropriados para idosos segundo os Critérios de Beers: revisão sistemática. Cien Saude Colet. 2021; 26(8): 3209–19.
SANTOS GR DOS, et al. Atenção farmacêutica ao idoso na polifarmácia.. 2021; 7(5): 709-23.
STAUFFER SJ, et al. Potentially inappropriate medication use among older adults with lower-limb loss. Geriatr Nurs. Published online February 16, 2024.
STRAND LM, et al. pharmaceutical care practice. New York Mcgraw-Hill, 2012.
WERNLI U, et al. Prescription trends in hospice care: A longitudinal retrospective and descriptive medication analysis. Am J Hosp Palliat Care. 2023; 40(8): 820–8.
XU XJ e TAN MP. Anticholinergics and falls in older adults. Expert Rev Clin Pharmacol. 2022; 15(3): 285–94.
ZHU X, et al. Evaluation of potentially inappropriate medications for the elderly according to beers, STOPP, START, and Chinese criteria. Front Pharmacol. 2024; 14.