Abstract
Objective: To carry out an integrative review on the effectiveness of ultrasound-guided intra-articular infiltrations in the treatment of pain in patients with knee osteoarthritis. Methods: This is an integrative review study. The sample was composed of scientific works that answered the research question and data collection was carried out in February 2024. Results: It was found that oral treatment for KOA is not sufficient to control the disease and, for this reason, the Prescription of intra-articular infiltration has been satisfactory, especially when guided by ultrasound. Infiltrations improve rigidity, functional capacity and mobility. Furthermore, they provide greater comfort, well-being and quality of life for the individual with KOA. Conclusion: ultrasound-guided intra-articular infiltrations are more efficient than other pharmacological modalities, as they significantly reduce pain complaints over a longer period, improve stiffness, functional capacity, mobility and ensure greater comfort and well-being for patients with KOA. and quality of life. Furthermore, ultrasound-guided intra-articular infiltrations are performed in a safer and more effective way.
References
ABRAMOFF B; CALDERA, FE. Osteoarthritis: pathology, diagnosis, and treatment options. Med. Clin. North Am., 2020; 104 (2):293-311.
AKESEN S; AKESEN B; ATICI, Teoman; GURBET, Alp; ERMUTLU, Cenk; OZYALCIN, Ali. Comparison of efficacy between the genicular nerve block and the popliteal artery and the capsule of the posterior knee (IPACK) block for total knee replacement surgery: a prospective randomized controlled study. Acta Orthopaedica Et Traumatologica Turcica, 2021; 55( 2): 134-140.
BENNELL KL, et al.Effect of Intra-articular Platelet-Rich Plasma vs Placebo Injection on Pain and Medial Tibial Cartilage Volume in Patients With Knee Osteoarthritis. Jama, [S.L.], 2021; 326 (20): 2021-23.
CHENG AW; BOLOGNESI M; KRAUS VB. DIO2 modifies inflammatory responses inchondrocytes. Osteoarthritis Cartilage, 2012; 20(5):440-5.
EVANIEW N, SIMUNOVIC N, KARLSSON J. Cochrane in CORR®: Viscosupplementation for the treatment of osteoarthritis of the knee. Clin Orthop Relat Res, 2014; 472(07):2028–2034
FERNÁNDEZ-CUADROS ME. Ozone fundamentals and effectiveness on Knee pain: Chondromalacia and Knee Osteoarthritis. LAP LAMBERT Academic Publishing. 2016.
FILARDO G, et al. PRP Injections for the Treatment of Knee Osteoarthritis: a meta-analysis of randomized controlled trials. Cartilage, [S.L.], 2020; 13 (1): 364-375.
FREITAS LS. Exercícios domiciliares para alívio da dor em pacientes com osteoartrite de joelho: revisão sistemática. 2020. Trabalho de Conclusão de Curso (Bacharel em Fisioteraia). Faculdade de Ceilândia. Universidade de Brasília, Brasília, 2020;36p.
GHAI B, et al. Effectiveness of platelet rich plasma in pain management of osteoarthritis knee: double blind, randomized comparative study. Brazilian Journal Of Anesthesiology (English Edition), [S.L.], 2019; 69 (5): 439-447.
HAMEED F e IHM J. Injectable medications for osteoarthritis. PMR, 2012;4(5, Suppl)e75–e81.
TROUVIN AP e PERROT S. Pain in osteoarthritis. Implications for optimal management. Joint Bone Spine, 2018; 85(4):429-434.
KAMPITAK W et al. Effect of ultrasound-guided selective sensory nerve blockade of the knee on pain management compared with periarticular injection for patients undergoing total knee arthroplasty: a prospective randomized controlled trial. The Knee, [S.L.], 2021; 33: p.1-10.
LUNDSTROM ZT, SYTSMA TT, GREENLUND LS. Rethinking Viscosupplementation: Ultrasound- Versus Landmark-Guided Injection for Knee Osteoarthritis. J Ultrasound Med. 2020; 39(1):113-117.
OO WM, et al. Inflammatory ultrasound features as prognostic factors of pain and functional outcomes following intra‐articular platelet‐rich plasma in knee osteoarthritis. International Journal Of Rheumatic Diseases, [S.L.], 2023; 26 (8): p. 1540-1546.
PAGE MJ, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ. 2021;372.
RAEISSADAT SA, et al. The comparison effects of intra-articular injection of Platelet Rich Plasma (PRP), Plasma Rich in Growth Factor (PRGF), Hyaluronic Acid (HA), and ozone in knee osteoarthritis; a one year randomized clinical trial. Bmc Musculoskeletal Disorders, [S.L.], 2021; 22 (1):1.
RODRIGUES TA, et al. Pain management in patients with knee osteoarthritis by ultrasound-guided genicular nerve block. Case reports. Brazilian Journal Of Pain, [S.L.], 2020; 3 (3):1.
RAHMATI M, MOBASHERI A, MOZAFARI M. Inflammatory mediators in osteoarthritis: A critical review of the state-of-the-art, current prospects, and future challenges. Bone, 2016; 85: 81-90.
SAMUEL AJ; KANIMOZHI D. Item generation and domain and item content validation for the individual with knee osteoarthritis: a mixed-method study. Research in Physiotherapy Journal, 2021; 11(1):11-31.
SAWITZKE AD, et al. Effect of Pulsed Low-Intensity Ultrasonography on Symptom Relief and Tibiofemoral Articular Cartilage Thickness Among Veterans Affairs Enrollees With Knee Osteoarthritis. Jama Network Open, [S.L.], 2022; 5(3): e220632.
SEYAM O, et al. Clinical utility of ozone therapy for musculoskeletal disorders. Med. Gas. Res., 2018; 8 (3): 103-110.
SMITH C, et al. Combined intra-articular injection of corticosteroid and hyaluronic acid reduces pain compared to hyaluronic acid alone in the treatment of knee osteoarthritis. Knee Surg. Sports Traumatol. Arthrosc., 2019; 27(6):1974-1983.
SOUZA MT; SILVA MD, CARVALHO R. Revisão integrativa: o que é e como fazer. einstein. 2010; 8 (1Pt 1):102-6
TSCHOPP M, et al. A Randomized Trial of Intra-articular Injection Therapy for Knee Osteoarthritis. Investigative Radiology, [S.L.], 2022; 58 (5): 355-362, 27 dez. 2022.
WANG C-C et al. Effect of ultrasound-detected synovitis on therapeutic efficacy of hyaluronic acid injection for symptomatic knee osteoarthritis. Rheumatology, 2021; 60(10): 4486-4494, 2021.
