Abstract
Objective: To report a case of Castleman’s disease in axillary area, which is a rare lymphoproliferative disorder, and to review clinical and therapeutic aspects of the disease, emphasizing the importance of its differential diagnosis with infectious and neoplastic pathologies. Case report: It is an asymptomatic patient with palpable mammary and axillary nodules, which are considered suspicious to the ultrasound, they were submitted to a core biopsy and aspiration puncture, respectively, and they were benign after the microscopy. However, an axillary nodule excision was performed due to significant growth on clinical and ultrasound examination after six months of medical monitoring, and the diagnosis of Castleman’s disease was concluded after histopathological and immunohistochemical studies. Final considerations: Although rare, the diagnosis of this disease should always be made in the face of lymphoproliferative disorders, due to the clinical and radiological similarities with several infectious and malignant diseases. The patient had a localized disease, then the exeresis of the lesion provides a diagnostic support and represents a curative treatment.