Keywords
Endometrial neoplasms
Endometrium
Levonorgestrel
Endometrial cancer
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Abstract
Objective: To conduct a comprehensive literature review on endometrial cancer and its relationship with the Levonorgestrel-releasing Intrauterine Device (LNG-IUD), evaluating its potential as a protective factor in the prevention of this neoplasm. Methods: An exploratory quantitative research, in the form of a literature review, was conducted using the PubMed Medline, BVS, ScienceDirect (Elsevier), and CAPES Periodicals Portal databases. Terms used: "LNG-IUD," "Endometrial cancer," "Cancer risk," "Levonorgestrel," "Intrauterine Devices," "Endometrial Neoplasms," "Endometrium," and "Levonorgestrel." Relevant articles available for public access were selected. Results: In PubMed, ten articles indicated that the LNG-IUD induces endometrial changes, significantly reducing bleeding and cellular proliferation. In the CAPES Periodicals Portal, ten articles showed that the LNG-IUD is associated with a lower incidence of endometrial cancer, especially in obese women. In BVS, four articles confirmed the effectiveness of the LNG-IUD in treating endometrial hyperplasia, being an effective alternative to oral progestogens. Conclusion: The Levonorgestrel-releasing Intrauterine Device may play an important role in the prevention and treatment of endometrial cancer, reducing cancer risk and promoting the regression of endometrial hyperplasia.
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