Keywords
Tumor Resection
Adjuvant Therapies
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Abstract
Objective: To analyze the limitations of surgical approaches in the treatment of astrocytomas and oligodendrogliomas, based on advances in the molecular understanding of these tumors and technological innovations in neurosurgery. Method: An integrative review was conducted. The search was performed in the PubMed Central (PMC) database, and after applying inclusion and exclusion criteria, 12 articles were selected. Results: The studies reveal that surgical resection is the main therapeutic approach for these tumors, although complete removal is limited, especially when located in eloquent brain areas. Advances such as neuronavigation and intraoperative monitoring have improved the precision of resections, but tumor recurrence, particularly in high-grade gliomas, remains a major challenge. The use of adjuvant therapies, including personalized radiotherapy and chemotherapy, is crucial to improving patient survival. Conclusions: The infiltrative nature of these tumors and the risks associated with surgeries in functional brain areas highlight the need to balance the extent of resection with the preservation of brain functionality. New approaches, such as laser interstitial thermal therapy (LITT) and the use of advanced intraoperative technologies, should be the focus of future research.
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