Keywords
Epidemiology
AIDS
Mortality
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Abstract
Objective: To analyze the temporal trend of AIDS mortality in Brazil, enabling the identification of different patterns between regions and states. Methods: This is an ecological study, with time series analysis techniques, of AIDS-related deaths, registered in the Mortality Information System from 2001 to 2023. Time trend analyses were performed by sex, race/color, age group, region and federative unit of residence, using the Joinpoint Regression software. The study used publicly accessible secondary data and respected the aspects of resolution no. 466 of the National Health Council. Results: During the period, there were 265,935 AIDS deaths in Brazil, predominantly in the age group of 30 to 49 years (59.3%) and in males (66.8%). The country showed a decreasing trend (AAPC=- 0.74) in the AIDS mortality rate for both sexes. In the south and southeast regions, the trend was decreasing, while in the north and northeast regions, the trend was increasing. Conclusion: Differentiated patterns were identified in the trend of AIDS mortality in the country, highlighting the need for policies that understand and consider these differences, so that we can ensure equity in a country of vast size and great inequalities.
References
ALVAREZ-URIA G. Factors associated with delayed entry into HIV medical care after HIV diagnosis in a resource-limited setting: Data from a cohort study in India. PeerJ. 2013; 18(1):e90.
AGOSTINI R, et al. A resposta brasileira à epidemia de HIV/AIDS em tempos de crise. Ciência & Saúde Coletiva [online], 2019; 24(12): 4599-4604.
BAKER JV, et al. Changes in inflammatory and coagulation biomarkers: a randomized comparison of immediate versus deferred antiretroviral therapy in patients with HIV infection. Journal of Acquired Immune Deficiency Syndromes, 2011; 56(1): 36-43.
BRASIL. Ministério da Saúde. Guia para certificação da eliminação da transmissão vertical de HIV, Sífilis, Hepatite B e Doença de Chagas. 2024. Disponível em: https://www.gov.br/aids/pt-br/central-de-conteudo/publicacoes/2023/guia_versao-preliminar.pdf/view. Acessado em: 01 de dezembro de 2024.
CASTRO L, et al. Epidemiologia da mortalidade pelo HIV/AIDS no Brasil entre os anos de 2016 e 2021: uma revisão integrativa. Revista Eletrônica Acervo Saúde, 2022; 15 (9): 2178-2091.
CHAPIN-BARDALES J, et al. Trends in racial/ethnic disparities of new AIDS diagnoses in the United States, 1984-2013. Annals of Epidemiology, 2017; 27(5): 329-334.
CUNHA APD, et al. Analysis of the trend of mortality from HIV/AIDS according to sociodemographic characteristics in Brazil, 2000 to 2018. Ciências & Saúde Coletiva, 2022; 27(3):895-908.
FRANCO KB, et al. Analysis of deaths due to acquired immunodeficiency syndrome. Revista da Rede de Enfermagem do Nordeste, 2017; 18(4): e33605.
FONSECA MGP, et al. AIDS mortality, "race or color," and social inequality in a context of universal access to highly active antiretroviral therapy (HAART) in Brazil, 1999-2004. Cadernos de Saúde Pública, 2007; 23(Sup 3):S445-S455.
GAO D, et al. Secular trends in HIV/AIDS mortality in China from 1990 to 2016: Gender disparities. PLOS ONE, 2019; 14(7): e0219689.
CARTER A, et al. Global, regional, and national burden of HIV/AIDS, 1990-2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021. Lancet HIV, 2024; 11(12):e807-e822.
GOLUCCI APBS, et al. Influence of AIDS antiretroviral therapy on the growth pattern. Jornal de Pediatria, 2019; 95(1):7-17.
GOMES D, et al. AIDS-related mortality in Pará Province, Brazilian Amazon region: Spatial and temporal analysis. PLoS One, 2023;18(1):e0279483.
GOVENDER RD, et al. Global Epidemiology of HIV/AIDS: A Resurgence in North America and Europe. J Epidemiol Glob Health, 2021; 11(3):296-301.
GRAEFF SVB, et al. Evolução da infecção pelo HIV entre os povos indígenas do Brasil Central. Cadernos de Saúde Pública, 2021; 37(12): :e00062920.
GRATÃO LHA, et al. Effects of HAART in the nutritional status of children and adolescents infected by HIV in Brazil: a systematic review. Ciências & Saúde Coletiva, 2021; 26(4):1346-1354.
HAEUSER E, et al. Local Burden of Disease sub-Saharan Africa HIV Prevalence Collaborators. Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000-2018. BMC Medicine, 2022; 20(1):488.
IBGE. Instituto Brasileiro de Geografia e Estatística. IBGE. Censo Brasileiro de 2022. Rio de Janeiro: IBGE, 2022. Disponível em: https://www.ibge.gov.br/estatisticas/sociais/populacao/9109-projecao-da-populacao.html?edicao=41053. Acessado em: 20 de novembro de 2024.
JIANG Y, et al. A meta-analysis of the efficacy of HAART on HIV transmission and its impact on sexual risk behaviours among men who have sex with men. Sci Rep, 2020;10(1):1075.
KIM HJ, et al. Permutation tests for joinpoint regression with applications to cancer rates. Stat Med, 2000; 19(3):335-351.
LUNA LS, et al. AIDS mortality in Brazil, 2012-2022: a time series study. AIDS Res Ther, 2024; 21(1):80.
REN N, et al. Patterns of HIV or AIDS Mortality Among Older People From 1990 to 2019 in China: Age-Period-Cohort Analysis. JMIR Public Health Surveill, 2022; 8(11):e35785.
REBEIRO PF, et al. Trends and Disparities in Mortality and Progression to AIDS in the Highly Active Antiretroviral Therapy Era: Tennessee, 1996–2016. American Journal of Public Health, 2019; 109(9):1266-1272.
ROSSI SMG, et al. Impacto da terapia antirretroviral conforme diferentes consensos de tratamento da Aids no Brasil. Rev Panam Salud Publica, 2012;32(2):117–123.
SÃO PAULO. Secretaria Municipal de Saúde. Boletim Epidemiológico de HIV/AIDS e Sífilis. 2024. Disponível em: https://capital.sp.gov.br/web/saude/w/istaids/245476. Acessado em: 12 de dezembro de 2024.
SHU R, et al. Trends in HIV/AIDS-Related Mortality and the Impact of Antiretroviral Treatment Strategies in Lu'an City: A Comprehensive Analysis. Med Sci Monit, 2024; 30: e944727.
UNAIDS. RELATÓRIO GLOBAL SOBRE AIDS 2024 – RESUMO EXECUTIVO. Disponível em: https://unaids.org.br/wp-content/uploads/2024/07/RelatorioGlobalPTBR.pdf. Acessado em: 20 de novembro de 2024
WHO. Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring: recommendations for a public health approach. 2021. Disponível em: https://www.ncbi.nlm.nih.gov/books/NBK572729/pdf/Bookshelf_NBK572729.pdf. Acessado em: 23 de novembro de 2024.
WHO. HIV statistics, globally and by WHO region, 2024. 2024. Disponível em: https://cdn.who.int/media/docs/default-source/hq-hiv-hepatitis-and-stis-library/j0482-who-ias-hiv-statistics_aw-1_final_ys.pdf?sfvrsn=61d39578_3. Acessado em: 20 de novembro de 2024.
ZHAI M, et al. The trend of AIDS in China: A prediction and comparative analysis with G20 countries based on the Global Burden of Disease Study 2019. J Glob Health, 2024; 14: 04029.