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Epididymitis associated with Dengue
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Keywords

Dengue-associated epididymitis
Viral epididymitis management
Genitourinary manifestations in dengue
Infertility risk in viral infections

How to Cite

Epididymitis associated with Dengue. (2025). Electronic Journal Collection Health, 25, e19830. https://doi.org/10.25248/reas.e19830.2025

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Abstract

Objective: Describe a rare case of dengue-associated epididymitis, emphasizing its presentation, diagnosis, treatment, and prognosis, aiming to enhance awareness among healthcare professionals. Case details: A 27-year-old male with no prior comorbidities presented with a 7-day history of fever, myalgia, anorexia, and a positive dengue IgM test, followed by 24-hour onset of unilateral testicular pain. Physical examination revealed a painful, engorged left epididymis without scrotal erythema or nodules. Scrotal ultrasound with Doppler confirmed epididymitis, with no bacterial infection detected in urinalysis or culture. The patient received symptomatic treatment, including analgesics and hydration, and was monitored for symptom progression. The patient achieved full symptomatic resolution within five days of conservative treatment. A semen analysis conducted one month post-recovery demonstrated normal parameters, indicating no lasting impact on fertility. The clinical presentation of epididymitis was attributed to dengue infection, supported by exclusion of other common etiologies. Final considerations: A rare manifestation of dengue is evidenced, including epididymitis in its clinical spectrum. Diagnosis requires a detailed history, physical examination, and imaging to differentiate it from other causes of acute scrotum. Awareness of this association is crucial for prompt identification and management, ensuring favorable outcomes.

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References

ANWAR F, et al. Epidemiological and hematological investigation of dengue virus infection. Microbiology and Immunology, 2022; 66(9): 426-432.

ARORA SK, et al. Predictors of severe dengue amongst children as per the revised WHO classification. Journal of Vector Borne Diseases, 2021; 58(4): 329-334.

BHATT S, et al. The global distribution and burden of dengue. Nature, 2013; 496(7446): 504-507.

CARAGATA EP, et al. Prospects and pitfalls: next-generation tools to control mosquito-transmitted disease. Annual review of microbiology, 2020; 74(1): 455-475.

CHEN L, et al. Ultrasound Imaging Findings of Acute Testicular Infection in Patients With Coronavirus Disease 2019: A Single‐Center–Based Study in Wuhan, China. Journal of Ultrasound in Medicine, 2021; 40(9): 1787-1794.

CHEN T, et al. Dengue hemorrhagic fever complicated with acute idiopathic scrotal edema and polyneuropathy. American Journal of Tropical Medicine and Hygiene, 2008; 78(1): 8.

ENDY TP, et al. Epidemiology of inapparent and symptomatic acute dengue virus infection: a prospective study of primary school children in Kamphaeng Phet, Thailand. American journal of epidemiology, 2002; 156(1): 40-51.

FAION AG, et al. Epididimite Relacionada a Infecção por Coronavírus: Relato de Caso e Revisão da Literatura. Revista Urominas, 2021; 30130: 140.

FIGUEIRÓ AC, et al. Óbito por dengue como evento sentinela para avaliação da qualidade da assistência: estudo de caso em dois municípios da Região Nordeste, Brasil. Cadernos de Saúde Pública, 2008; 27: 2373-2385.

HUNSPERGER EA, et al. Performance of dengue diagnostic tests in a single-specimen diagnostic algorithm. The Journal of infectious diseases, 2016; 214(6): 836-844.

KESHARWANI A, et al. A case of dengue fever associated with acute scrotal oedema. Australasian Medical Journal (Online), 2021; 14(10): 259-262.

LALLE E, et al. Prolonged detection of dengue virus RNA in the semen of a man returning from Thailand to Italy, January 2018. Eurosurveillance, 2018; 23(18): 18-00197.

LAMBRECHTS L, et al. Direct mosquito feedings on dengue-2 virus-infected people reveal dynamics of human infectiousness. PLoS Neglected Tropical Diseases, 2023; 17(9): 11593.

MERLOS F, et al. Relato de Caso: Dengue-Encefalite e Morte Encefálica Uma Complicação Rara. Revista Foco, 2024; 17(10): 6024.

MONS J, et al. Effects of acute dengue infection on sperm and virus clearance in body fluids of men. Emerging Infectious Diseases, 2022; 28(6): 1146.

NEDJADI T, et al. Tackling dengue fever: Current status and challenges. Virology journal, 2015; 12: 1-11.

NGUYEN NM, et al. A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients. The Journal of infectious diseases, 2013; 207(9): 1442-1450.

ROSSI P, et al. Mutual exclusion of Asaia and Wolbachia in the reproductive organs of mosquito vectors. Parasites & vectors, 2015; 8: 1-10.

SHEPARD DS, et al. The global economic burden of dengue: a systematic analysis. The Lancet infectious diseases, 2016; 16(8): 935-941.

SOJOS BYB, et al. Fisiopatología del dengue. Recimundo, 2019; 3(3): 622-642.

STANAWAY JD, et al. The global burden of dengue: an analysis from the Global Burden of Disease Study 2013. The Lancet infectious diseases, 2016; 16(6): 712-723.

YUAN K, et al. Risk and predictive factors for severe dengue infection: a systematic review and meta-analysis. PLoS One, 2019; 17(4): 267186.