Abstract
Objective: Describe the profile of the pediatric population with Down syndrome (DS) hospitalized with severe acute respiratory syndrome (SARS) due to COVID-19 in the first 3 years of the pandemic in Brazil. Methods: Study of epidemiological surveillance with data from the Influenza and other respiratory virus surveillance network (SIVEP-GRIPE) between February 2020 and December 2022. The variables included were demographic data, comorbidities, symptoms, length of hospitalization, admission to the Intensive Care Unit (ICU), days of ICU stay, use of ventilatory support, and case outcomes. Results: The records of 1,570,446 cases hospitalized for SARS, with a positive test for COVID-19 and known outcomes were evaluated. Of these, 658 patients (0.04%) were pediatric patients with DS. Over the 3 years, most of the individuals evaluated were white and lived in the southeast region, with no predominance between genders. There was no variation over the years regarding the comorbidities presented by the patients and the symptoms at admission. Conclusion: Over the first 3 years of the pandemic, the clinical picture presented by patients hospitalized for SARS-CoV-2 SARS was similar.
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