Keywords
Cancer
Antineoplastics
Quality of life
How to Cite
Copyright © | All rights reserved.
The journal holds the exclusive copyright for the publication of this article under the terms of Brazilian law 9610/98.
Partial reproduction
The use of parts of the texts, figures and questionnaire of the article is free, being mandatory the citation of the authors and journal.
Total reproduction
It is expressly prohibited and must be authorized by the journal.
Abstract
Objective: To evaluate the quality of life (QoL) of children and adolescents with oral mucositis (OM) undergoing chemotherapy. Methods: Analytical observational, cross-sectional, and quantitative study involving 30 patients aged 0 to 19 years hospitalized at the Alcides Carneiro University Hospital (HUAC) in Campina Grande. Data were collected using the World Health Organization (WHO) scale and the sociodental indicator Oral Impact on Daily Performances (OIDP). Results: Cancer prevalence was higher in males (63.3%), with a similar distribution among white and mixed-race individuals (46.7%). A higher proportion of married parents (46.7%), high school education (43.3%), and income between 1 and 3 minimum wages (56.7%) was observed. The OIDP questionnaire identified oral health impacts before and between 7 to 10 days after the chemotherapy cycle. The most prevalent oral diseases were cavities (13.3%) in the first assessment and mouth sores (16.7%) in the second. OM had the highest prevalence at grade I (40%) and was more severe in male patients. Conclusion: OM significantly impacts patients' QoL, affecting their ability to eat and speak, causing pain and discomfort, which may lead to treatment interruption.
References
ALBUQUERQUE RA, et al. Protocolo de atendimento odontológico a pacientes oncológicos pediátricos – revisão de literatura. Rev Odontol Unesp, 2007; 36(3): 275-80.
ALVES LDB, et al. Toxicidades orais da terapia oncológica em crianças e adolescentes: um estudo descritivo. CES Odontología, 2021; 34(2): 30-45.
CUNHA CB. Avaliação da eficácia do tratamento para mucosite oral induzida por cinco-fluoracil, com uso de laser de baixa potência em diferentes comprimentos de onda. São Paulo: Universidade de São Paulo, Faculdade de Odontologia, 2010.
CURRA M, et al. Protocolos quimioterápicos e incidência de mucosite bucal. Revisão integrativa. Einstein (São Paulo), 2018; 16(1): 1-9.
DAMASCENA LC, et al. Severe oral mucositis in pediatric cancer patients: survival analysis and predictive factors. International Journal of Environmental Research and Public Health, 2020; 17(4): 1235.
EPSTEIN JB e SCHUBERT MM. Oropharyngeal mucosites in cancer therapy. Review of pathogenesis, diagnosis and management. Oncology (Williston Park), 2003; 17: 1767.
GUIMARÃES JR, et al. The incidence of severe oral mucositis and its occurrence sites in pediatric oncologic patients. Medicina Oral, Patología Oral y Cirugía Bucal, 2021; 26(3): e299.
GUSHI LL, et al. Fatores associados ao impacto das condições de saúde bucal nas atividades de vida diária de adolescentes, Estado de São Paulo, 2015. Revista Brasileira de Epidemiologia, 2020; 23: 1-9.
JUNQUEIRA LC e CARNEIRO J. Histologia básica. Rio de Janeiro: Guanabara Koogan; 2008.
LIMA, et al. Qualidade de Vida e Saúde Bucal em Crianças submetidas à Terapia Antineoplásica. Revista Brasileira de Cancerologia, 2022; 68(2).
NEVES LJ, et al. Avaliação do efeito do laser preventivo na mucosite oral quimioinduzida em pacientes submetidos a altas doses de Metotrexato. Revista Brasileira de Cancerologia, 2021; 67(1).
NEVES LJ, et al. Avaliação do efeito do laser preventivo na mucosite oral quimioinduzida em pacientes submetidos a altas doses de Metotrexato. Revista Brasileira de Cancerologia, 2021; 67(1).
ORCINA BF, et al. Prevalência de Manifestações Bucais em Pacientes com Câncer Assistidos em um Programa de Atenção Domiciliar na Cidade de Pelotas-RS. Revista Brasileira de Cancerologia, 2021; 67(2): e–081184.
PIRES HF, et al. Occurrence and severity of oral mucositis in Brazilian pediatric cancer patients. Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2020; 20: e5621.
SANTOS PSS, et al. Mucosite oral: perspectivas atuais na prevenção e tratamento. RGO, 2009; 57(3): 339-44.
SANTOS PSS e SOARES Jr LAV. Medicina bucal: a prática na odontologia hospitalar. São Paulo: Santos; 2012.
SINGH V e SINGH AK. Oral mucositis. National Journal of Maxillofacial Surgery, 2020; 11(2): 159.
TROTTI A, et al. Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature review. Radiother Oncol, 2003; 66(3): 253-62.
VALDUGA F, et al. Prevenção da Mucosite Oral em Pacientes submetidos à Quimioterapia. Revista Brasileira de Cancerologia, 2018; 64(2): 189-94.
VOLPATO LER, et al. Mucosite bucal radio e quimioinduzida. Rev Bras Otorrinolaringol, 2007; 73(4): 562-8.